{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:34:25Z","timestamp":1777642465045,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>\n                    The global incidence of human infections associated with extended-spectrum \u03b2-lactamase (ESBL)-producing\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    is increasing. Dairy animals are reservoirs of ESBL-producing\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    , especially, third-generation cephalosporin (3GC)-resistant strains. To further understand the diversity of 3GC-resistant\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    across animals of different age groups (e.g., pre- and postweaned calves, lactating cows, and dry cows) and farms, we used pulsed-field gel electrophoresis (PFGE) to characterize 70 fecal isolates from 14 dairy farms located in nine Pennsylvania counties. Results of this analysis indicated that 3GC-resistant\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    were highly diverse and grouped into 27 PFGE clades (80% similarity cutoff) and 24 unique antimicrobial resistance patterns were observed among the isolates. For eight farms, clonal\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    with the same resistance patterns were isolated from two or more age groups, indicating that strains were carried in both the calves and adult cows within the same herd. However, there were also several isolates with the same resistance pattern that were distributed to different clades, including isolates from different animal age groups on the same farm, suggesting different strains of\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    within a farm harbored the same resistance-conferring elements. Results of this analysis indicated that 3GC-resistant\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    were highly diverse, associated with multidrug resistance, and circulated through different (noncommingled) animal groups on individual farms.\n                  <\/jats:p>","DOI":"10.1089\/fpd.2018.2579","type":"journal-article","created":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T14:57:37Z","timestamp":1549292257000},"page":"368-370","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Diversity of Extended-Spectrum Cephalosporin-Resistant\n                    <i>Escherichia coli<\/i>\n                    in Feces from Calves and Cows on Pennsylvania Dairy Farms"],"prefix":"10.1177","volume":"16","author":[{"given":"Serajus","family":"Salaheen","sequence":"first","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huilin","family":"Cao","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakeitha L.","family":"Sonnier","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seon Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura P.","family":"Del Collo","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernest","family":"Hovingh","sequence":"additional","affiliation":[{"name":"Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey S.","family":"Karns","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradd J.","family":"Haley","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo Ann S.","family":"Van Kessel","sequence":"additional","affiliation":[{"name":"Environmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, USDA-ARS, Beltsville, Maryland."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,6]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.14.4.933-951.2001"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2018.2519"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004776"},{"key":"e_1_3_2_5_1","unstructured":"Food and Drug Administration. Summary Report on Antimicrobials Sold or Distributed for Use in Food-Producing Animals. 2014. Available at: http:\/\/www.fda.gov\/downloads\/ForIndustry\/UserFees\/AnimalDrugUserFeeActADUFA\/UCM416983.pdf accessed January27 2019."},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiw013"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00373-12"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2006.3.59"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2008.0201"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-12-263"}],"container-title":["Foodborne Pathogens and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/fpd.2018.2579","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/fpd.2018.2579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/fpd.2018.2579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:23:11Z","timestamp":1777443791000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/fpd.2018.2579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1089\/fpd.2018.2579"],"URL":"https:\/\/doi.org\/10.1089\/fpd.2018.2579","relation":{},"ISSN":["1535-3141","1556-7125"],"issn-type":[{"value":"1535-3141","type":"print"},{"value":"1556-7125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5]]}}}