{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:35:30Z","timestamp":1777642530519,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2020,11]]},"abstract":"\n In this study, we explored the prevalence of oxacillin-susceptible\n mecA<\/jats:italic>\n -positive\n Staphylococcus aureus<\/jats:italic>\n (OS-MRSA) in staphylococcal food poisoning outbreak isolates and foodborne isolates, and then investigated their molecular characteristics, classical staphylococcal enterotoxins (SEs), and drug resistance. Eight (2.9%) of 275 isolates from food poisoning outbreaks and 7 (3.8%) of 184 isolates from retail foods were identified as OS-MRSA isolates. Among the 15 OS-MRSA isolates, the most frequently detected toxin genes were\n hld<\/jats:italic>\n (100%),\n hla<\/jats:italic>\n (93.3%),\n pvl<\/jats:italic>\n (80.0%), and\n hlb<\/jats:italic>\n (46.7%) followed by\n seg<\/jats:italic>\n and\n seq<\/jats:italic>\n (33.3%, each),\n hlg<\/jats:italic>\n (26.7%),\n seb<\/jats:italic>\n and\n hlgv<\/jats:italic>\n (20.0%, each),\n sec<\/jats:italic>\n ,\n seh<\/jats:italic>\n ,\n sel<\/jats:italic>\n ,\n sep<\/jats:italic>\n , and\n tst<\/jats:italic>\n (13.3%, each), and\n sei<\/jats:italic>\n ,\n sem<\/jats:italic>\n ,\n sen<\/jats:italic>\n , and\n seo<\/jats:italic>\n (6.7%, each). None of isolates carried other tested virulence genes. The most frequently detected classical SEs were SEB and SEC (26.7%, each), followed by SEA and SEE (20.0%, each), and SED (6.7%). Resistance was most frequently observed in ampicillin, penicillin, and cefoxitin (100%, each), followed by trimethoprim\/sulfamethoxazole (93.3%), erythromycin (73.3%), amoxicillin\/clavulanic acid (46.7%), tetracyclines (26.7%), and ciprofloxacin (6.7%). All isolates were susceptible to other tested antibiotics. A dominant molecular type belonged to ST398-IVa-t034 (26.7%), followed by ST59-IVa-t437 (20.0%), ST88-III-t14340 and ST1-IVa-t114 (13.3%, each), and ST5-II-t002, ST630-t4549, ST5-II, and ST4495-t10738 (6.7%, each). Our findings indicated that OS-MRSA strains had a low prevalence rate among outbreak strains and foodborne strains, which frequently harbored SCCmec IVa, and carried a variety of toxin genes, and also expressed numerous classical SEs. In addition, all OS-MRSA isolates were susceptible to the majority of antibacterial agents except\n \u03b2<\/jats:italic>\n -lactam. Our study is the first to report that OS-MRSA isolates are associated with food poisoning outbreaks worldwide.\n <\/jats:p>","DOI":"10.1089\/fpd.2019.2774","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T12:15:25Z","timestamp":1595852125000},"page":"728-734","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Characterization of Oxacillin-Susceptible\n mecA<\/i>\n -Positive\n Staphylococcus aureus<\/i>\n from Food Poisoning Outbreaks and Retail Foods in China"],"prefix":"10.1177","volume":"17","author":[{"given":"Pengfei","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Miao","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luhong","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baozhong","family":"Cui","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebin","family":"Xu","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Shanghai Municipal Center for Disease Control & Prevention, Shanghai, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Congming","family":"Wu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, China Agricultural University, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Peng","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering, Northwest A&F University, Yangling, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,11,6]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2014.10.014"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins2071751"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2011.05.007"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1207-1405"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2672.2006.02957.x"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06711-11"},{"key":"e_1_3_4_8_1","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 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