{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:42:03Z","timestamp":1777642923226,"version":"3.51.4"},"reference-count":58,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>\n                    Brucellosis is a zoonotic infection caused by the consumption of contaminated raw milk and dairy products. This study aims to compare survival rates of\n                    <jats:italic toggle=\"yes\">Brucella abortus<\/jats:italic>\n                    RB51 and S19 vaccine strains to that of virulent\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    2308 strain during the manufacture of fresh and ripened cheeses. To do this, we inoculated fresh pasteurized milk with\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    RB51, S19, or 2308 at a 6\u2009\u00d7\u200910\n                    <jats:sup>8<\/jats:sup>\n                    colony-forming unit per milliliter concentration during the cheese making process. Cheese was manufactured at room temperature, then, fresh cheeses were conserved at either 4\u00b0C or 25\u00b0C for 7 days, while ripened cheeses were conserved for 31 days at the same temperatures. We measured\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    survival and pH values during different stages of the process. Our results confirm that all three strains can maintain viable cells in both types of cheeses throughout the process. Survival of\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    RB51 was 10 times lower than was the survival of the\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    S19 and\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    2308 strains in both fresh and ripened cheeses. Our results also suggest that both temperature and pH can condition\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    survival. In conclusion,\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    RB51 and S19 vaccine strains can survive throughout the manufacture and conservation processes of both fresh and ripened cheeses. In turn, this implies a potential health risk if cheeses contaminated with these strains were to be consumed.\n                  <\/jats:p>","DOI":"10.1089\/fpd.2022.0001","type":"journal-article","created":{"date-parts":[[2022,6,8]],"date-time":"2022-06-08T16:59:47Z","timestamp":1654707587000},"page":"535-542","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Survival of\n                    <i>Brucella abortus<\/i>\n                    RB51 and S19 Vaccine Strains in Fresh and Ripened Cheeses"],"prefix":"10.1177","volume":"19","author":[{"given":"Juan Carlos","family":"Ben\u00edtez-Serrano","sequence":"first","affiliation":[{"name":"Departamento de Microbiolog\u00eda e Inmunolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Palomares-Resendiz","sequence":"additional","affiliation":[{"name":"CENID Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efr\u00e9n","family":"D\u00edaz-Aparicio","sequence":"additional","affiliation":[{"name":"CENID Salud Animal e Inocuidad, Instituto Nacional de Investigaciones Forestales, Agr\u00edcolas y Pecuarias, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rigoberto","family":"Hern\u00e1ndez-Castro","sequence":"additional","affiliation":[{"name":"Departamento de Ecolog\u00eda de Agentes Pat\u00f3genos, Hospital General \u201cDr. Manuel Gea Gonz\u00e1lez\u201d, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Mart\u00ednez-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Laboratorio de Microbiolog\u00eda Aplicada, Facultad de Ciencias Qu\u00edmicas, Benem\u00e9rita Universidad Aut\u00f3noma de Puebla, Puebla, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Su\u00e1rez-G\u00fcemes","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda e Inmunolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3067-2719","authenticated-orcid":false,"given":"Beatriz","family":"Arellano-Reynoso","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda e Inmunolog\u00eda, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad de M\u00e9xico, M\u00e9xico."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2004.02.041"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-018-0108-1"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2859-5-13"},{"key":"e_1_3_5_5_1","unstructured":"[CDC] Center for Disease Control. People in four states may be drinking contaminated raw milk. Center for Disease Control and Prevention. Atlanta GA: USA Department of Health and Human Services 2017. Available at: https:\/\/www.cdc.gov\/media\/releases\/2017\/p1121-contaminated-raw-milk.html accessed March21 2022."},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods11050709"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0302.970219"},{"key":"e_1_3_5_8_1","unstructured":"Corbel MJ. Food and Agriculture Organization of the United Nations World Health Organization and World Organization for Animal Health. Brucellosis in humans and animals. WHO 2006. Available at: https:\/\/apps.who.int\/iris\/handle\/10665\/43597 accessed April23 2022."},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6709a4"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2018.12.009"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1935(17)36436-9"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.03.003"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.80921"},{"key":"e_1_3_5_14_1","first-page":"46","article-title":"Survival of Brucella abortus in the Mexican white soft cheese processing","volume":"2","author":"D\u00edaz-Cinco ME","year":"1998","unstructured":"D\u00edaz-Cinco ME, , Acedo-F\u00e9lix E, , Le\u00f3n D. Survival of Brucella abortus in the Mexican white soft cheese processing. Rec Res Dev Nutr Res, 1998; 2:46\u201357.","journal-title":"Rec Res Dev Nutr Res"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136696"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1990.11812504"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2010.11.033"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0307.12755"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0923-2508(96)80563-8"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41589-0"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2012.03.015"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7012(00)00241-4"},{"key":"e_1_3_5_23_1","first-page":"55","article-title":"Molecular identification of Brucella spp. in samples of fresh cow cheese in Veracruz [in Spanish]","volume":"52","author":"Hern\u00e1ndez-Carbajal GR","year":"2018","unstructured":"Hern\u00e1ndez-Carbajal GR, , Mart\u00ednez-Herrera DI, , Pard\u00edo-Sedas VT, , Quintana-Castro R, , L\u00f3pez-Hern\u00e1ndez KM, , Oliart-Ros RM, , Morales-\u00c1lvarez FF, , Villag\u00f3mez-Cort\u00e9s JA, , Huerta-Pe\u00f1a JC. Molecular identification of Brucella spp. in samples of fresh cow cheese in Veracruz [in Spanish]. Agrociencia, 2018; 52:55\u201366.","journal-title":"Agrociencia"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26678-0"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.05.084"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2019.01.022"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-384947-2.00137-9"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3134-5"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.2020.1868616"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21249341"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2003.08.002"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.4142\/jvs.2017.18.S1.281"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00609.x"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2017.01.043"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.17221\/344\/2015-CJFS"},{"key":"e_1_3_5_36_1","first-page":"479","article-title":"Identification of Brucella abortus S19 vaccinal strain in cow milk samples","volume":"37","author":"Mart\u00ednez-Chavarria LC","year":"2006","unstructured":"Mart\u00ednez-Chavarria LC, , Verdugo-Rodr\u00edguez A, , Hern\u00e1ndez-Castro R. Identification of Brucella abortus S19 vaccinal strain in cow milk samples. Vet M\u00e9x, 2006; 37:479\u2013486.","journal-title":"Vet M\u00e9x"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2011.0887"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.11.056"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1517-83822007000100005"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1051\/vetres:2003037"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2005.04.003"},{"key":"e_1_3_5_42_1","first-page":"147","article-title":"Vaccination against Brucella","volume":"13","author":"Nicoletti P","year":"1990","unstructured":"Nicoletti P. Vaccination against Brucella. Adv Biotechnol Processes, 1990; 13:147\u2013168.","journal-title":"Adv Biotechnol Processes"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.3923\/ijds.2009.142.151"},{"key":"e_1_3_5_44_1","first-page":"1","article-title":"Texture, physicochemical and sensory properties of artisanal Adobera cheese from Los Altos de Jalisco, a genuine Mexican cheese","volume":"70","author":"Ruvalcaba-G\u00f3mez JM","year":"2020","unstructured":"Ruvalcaba-G\u00f3mez JM, , Ruiz-Espinosa H, , Arteaga-Garibay RI, , Rojas-L\u00f3pez M, , Amador-Espejo GG, , Anaya-Esparza LM, , Delgado-Macuil RJ. Texture, physicochemical and sensory properties of artisanal Adobera cheese from Los Altos de Jalisco, a genuine Mexican cheese. Int J Dairy Technol, 2020; 70:1\u201310.","journal-title":"Int J Dairy Technol"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3506(75)80033-3"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01244-06"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2014.1823"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/jam.12226"},{"key":"e_1_3_5_49_1","volume-title":"Production of sheep and goat cheese","author":"Scholz W","year":"1997","unstructured":"Scholz W. Production of sheep and goat cheese [In Spanish]. Zaragoza, Spain: Acribia, 1997."},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(02)00255-9"},{"key":"e_1_3_5_51_1","author":"Smith JA","year":"2018","unstructured":"Smith JA. Brucella Lipopolysaccharide and pathogenicity: The core of the matter. Virulence, 2018;9;379\u2013382.","journal-title":"Virulence"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(06)72115-4"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.5433\/1679-0359.2016v37n5Supl2p3743"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01557"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.08.073"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-008-9003-6"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0307.12500"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(02)00232-8"},{"key":"e_1_3_5_59_1","first-page":"88","article-title":"Survival of Brucella abortus in milk fermented with a yoghurt starter culture","volume":"47","author":"Z\u00fa\u00f1iga-Estrada A","year":"2005","unstructured":"Z\u00fa\u00f1iga-Estrada A, , Mota-de la Garza L, , S\u00e1nchez-Mendoza M, , Santos-L\u00f3pez EM, , Filardo-Kerstupp S, , L\u00f3pez-Merino A. Survival of Brucella abortus in milk fermented with a yoghurt starter culture. Rev Latinoam Microbiol, 2005; 47:88\u201391.","journal-title":"Rev Latinoam Microbiol"}],"container-title":["Foodborne Pathogens and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/fpd.2022.0001","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/fpd.2022.0001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/fpd.2022.0001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:24:30Z","timestamp":1777443870000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/fpd.2022.0001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1089\/fpd.2022.0001"],"URL":"https:\/\/doi.org\/10.1089\/fpd.2022.0001","relation":{},"ISSN":["1535-3141","1556-7125"],"issn-type":[{"value":"1535-3141","type":"print"},{"value":"1556-7125","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8]]}}}