{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:43:30Z","timestamp":1777643010101,"version":"3.51.4"},"reference-count":60,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    is a primary cause of foodborne diseases, and the increasing prevalence of\n                    <jats:italic toggle=\"yes\">mcr-1-<\/jats:italic>\n                    carrying plasmids, which confer colistin resistance to\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    , poses significant global health concerns. As the frequency of occurrence of the\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    gene is increasing globally, we studied the prevalence of\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    in clinical\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates by analyzing 195 clinical strains isolated in 2020. Of the 195\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates, 41 isolates were resistant to colistin. We found\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    in two strains (\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Typhimurium ZJJX20006 and\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Kentucky ZJJX20014), which we analyzed in detail via whole-genome sequencing and antibiotic susceptibility testing. Two strains displayed resistance to ampicillin, ampicillin\u2013sulbactam, tetracycline, chloramphenicol, and cotrimoxazole, while ZJJX20006 displayed resistance to colistin and ZJJX20014 was sensitive. Genomic analysis revealed that these strains had plasmid-encoded\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    in IncHI2 plasmids, which were not similar to the\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    -IncX4 identified in 2016. These two strains also harbored other drug resistance genes, including\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>OXA-1<\/jats:sub>\n                    and\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-14<\/jats:sub>\n                    . Our findings may help clarify the molecular mechanisms of\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    dissemination among\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    strains in Jiaxing City and offer insights into the evolution of\n                    <jats:italic toggle=\"yes\">mcr-1<\/jats:italic>\n                    in\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1089\/fpd.2023.0051","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T17:02:06Z","timestamp":1694538126000},"page":"467-476","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristics of Two\n                    <i>mcr-1<\/i>\n                    -Harboring IncHI2 Plasmids from Clinical\n                    <i>Salmonella<\/i>\n                    Isolates in Jiaxing City"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6797-0798","authenticated-orcid":false,"given":"Miaomiao","family":"Jia","sequence":"first","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongwen","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Gao","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangming","family":"Sun","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Yan","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoying","family":"Zhu","sequence":"additional","affiliation":[{"name":"Jiaxing Key Laboratory of Pathogenic Microbiology, Jiaxing Center for Disease Control and Prevention, Jiaxing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,3]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx286"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky272"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10040812"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2017.08.018"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt282"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx327"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep08365"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.Es.2018.23.2.17-00821"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00853-19"},{"key":"e_1_3_4_11_1","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing","author":"CLSl","year":"2020","unstructured":"CLSl. 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