{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:18:38Z","timestamp":1777641518260,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foodborne Pathogens and Disease"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:p>\n                    Nutritional manipulations can reduce the detrimental effects of heat stress on animal health and production.\n                    <jats:italic toggle=\"yes\">Akkermansia muciniphila<\/jats:italic>\n                    (AM) is an innovative beneficial bacteria and can be used for conventional use as dietary supplements and pharmaceutical application. This study aimed to investigate the effects of administering AM on gut morphology, antioxidant indices, and gut microbiome of mice during heat stress. A total of 24 BALB\/c mice were randomly assigned to three groups including the control group (CON), heat stress group (HS), and AM administration under heat stress group (AM). Our results showed heat stress significantly increased the water consumption of mice. Administration of AM did not improve feed intake or weight gain. The serum levels of alanine aminotransferase and aspartate aminotransferase as well as antioxidant parameters were not different among the three groups. Heat stress decreased the jejunal villus height, and AM could reverse this effect. AM administration significantly increased the relative abundance of\n                    <jats:italic toggle=\"yes\">Verrucomicrobiota<\/jats:italic>\n                    at the phylum level. At the genus level, heat stress and AM groups tended to have a lower abundance of\n                    <jats:italic toggle=\"yes\">Alloprevotella<\/jats:italic>\n                    . In addition, AM tended to increase the relative abundance of\n                    <jats:italic toggle=\"yes\">[Eubacterium]_xylanophilum_group<\/jats:italic>\n                    in comparison with the other two groups. In summary, administration of AM can alleviate the damage of heat stress to the jejunum. However, it has no effect on serum antioxidant parameters, and its effect on the cecal microbiota is limited.\n                  <\/jats:p>","DOI":"10.1089\/fpd.2024.0046","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T04:23:51Z","timestamp":1722399831000},"page":"724-730","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of\n                    <i>Akkermansia muciniphila<\/i>\n                    on Gut Morphology, Antioxidant Indices, and Gut Microbiome of Mice Under Heat Stress"],"prefix":"10.1177","volume":"21","author":[{"given":"Caiyu","family":"Luo","sequence":"first","affiliation":[{"name":"School of Life Science and Engineering, Foshan University, Foshan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingzhu","family":"Du","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Foshan University, Foshan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rongxia","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Foshan University, Foshan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qien","family":"Qi","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Foshan University, Foshan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shumeng","family":"Luo","sequence":"additional","affiliation":[{"name":"The Hong Kong Polytechnic University, Hong Kong, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3986-3714","authenticated-orcid":false,"given":"Xin","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Life Science and Engineering, Foshan University, Foshan, 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