{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T15:31:46Z","timestamp":1782401506505,"version":"3.54.5"},"reference-count":28,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,11,6]],"date-time":"2020-11-06T00:00:00Z","timestamp":1604620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Facial Plastic Surgery &amp; Aesthetic Medicine"],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Importance:<\/jats:title>\n                    <jats:p>Functional septorhinoplasty (FSRP) has been shown to improve both global and disease-specific quality of life (QOL). However, the mechanism by which FSRP improves QOL has not been fully defined. We reasoned that NAO may impact sleep quality and, therefore, studied the relationship using validated patient-reported outcome measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate the correlation between NAO and sleep quality using Nasal Obstruction Symptom Evaluation (NOSE) and Functional Outcomes of Sleep Quality (FOSQ-10) questionnaires, and to evaluate the effect of FSRP on NAO and sleep quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, Setting, and Participants:<\/jats:title>\n                    <jats:p>This is a prospective longitudinal study of 125 patients undergoing FSRP for the repair of NAO between November 2017 and April 2019 in a university-based tertiary care medical center. The individuals (mean age\u2009=\u200938\u2009\u00b1\u200915.6 years, 65 females; 52%) were invited to complete the FOSQ-10 survey preoperatively and at 2, 4, 6, and 12 months postoperatively, and 122 of these patients also completed the NOSE questionnaire. Sixty individuals who reported a history of snoring also completed the Snoring Outcomes Survey (SOS). Twelve of 125 patients had obstructive sleep apnea. Patient demographics, nasal surgery, and medical histories and outcomes were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>Functional septorhinoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes and Measures:<\/jats:title>\n                    <jats:p>Comparison of pre- and postoperative sleep and NAO scores to determine the correlation between the severity of NAO and sleep quality and the impact of correction of NAO on sleep quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 125 patients completed FOSQ-10 questionnaire with a median score of 18.00 (IQR\u2009=\u200915.33\u201319.66) at baseline. Among these individuals, 122 patients completed the NOSE questionnaire with a median score of 65 (IQR\u2009=\u200945\u201375). A negative correlation between NOSE and FOSQ-10 scores was found at baseline (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.380,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There was a significant difference in baseline FOSQ-10 scores between individuals with (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200912, mean FOSQ-10 score\u2009=\u200913.28\u2009\u00b1\u20093.19) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and without sleep apnea (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009100, mean FOSQ-10 score\u2009=\u200917.24\u2009\u00b1\u20093.21).\n                    <\/jats:p>\n                    <jats:p>\n                      After FSRP, the NOSE and FOSQ-10 scores improved at each postoperative follow-up time point. The change in FOSQ-10 scores was statistically significant at months 2, 4, and 6 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) but not at month 12 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.161). The NOSE scores were statistically different from baseline level for each postoperative follow-up visits (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001\u2014months 2, 4, and 6 and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.031\u2014month 12). The distribution of NOSE scores was not different statistically (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.984). The negative correlation between NOSE and FOSQ-10 mean scores that was demonstrated at baseline increases postoperatively (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u20090.508,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance:<\/jats:title>\n                    <jats:p>FSRP can improve both symptoms of NAO and sleep quality. The increased correlation between NAO and sleep quality after surgery is consistent with the hypothesis that improvement in NAO improves sleep quality and QOL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/fpsam.2020.0005","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T23:23:56Z","timestamp":1589930636000},"page":"412-419","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["The Impact of Nasal Obstruction and Functional Septorhinoplasty on Sleep Quality"],"prefix":"10.1177","volume":"22","author":[{"given":"Anil","family":"Hismi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Massachussetts Eye and Ear, Boston, Massachussetts, USA."},{"name":"Department of Otolaryngology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phoebe","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Massachussetts Eye and Ear, Boston, Massachussetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Locascio","sequence":"additional","affiliation":[{"name":"Department of Neurology, Massachussetts General Hospital, Harvard Medical School, Boston, Massachussetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia A.","family":"Levesque","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Massachussetts Eye and Ear, Boston, Massachussetts, USA."},{"name":"Department of Otolaryngology, Harvard Medical School, Boston, Massachussetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin Williams","family":"Lindsay","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Massachussetts Eye and Ear, Boston, Massachussetts, USA."},{"name":"Department of Otolaryngology, Harvard Medical School, Boston, Massachussetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,11,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2003.09.016"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2015.0590"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23345"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.8.5.306"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000157831.46250.ad"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2015.1854"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2016.1410"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.128.7.819"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/smrv.2001.0220"},{"key":"e_1_3_3_11_2","volume-title":"Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem","author":"Institute of Medicine Committee on Sleep M, Research","year":"2006","unstructured":"Institute of Medicine Committee on Sleep M, Research. 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