{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:33:00Z","timestamp":1789421580486,"version":"build-2803163510"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T00:00:00Z","timestamp":1641168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Facial Plastic Surgery &amp; Aesthetic Medicine"],"published-print":{"date-parts":[[2022,2,1]]},"abstract":"<jats:sec>\n                    <jats:title>Importance:<\/jats:title>\n                    <jats:p>Reconstructing cosmetically sensitive defects in an aging population undergoing multiple Mohs micrographic surgeries (MMS) may be addressed with alternatives to surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Patients undergoing MMS with defect reconstruction in visually prominent areas receiving placental allograft were compared with traditional autologous tissue-based procedures\u2014flaps and full-thickness skin grafts (FTSG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, Setting, and Participants:<\/jats:title>\n                    <jats:p>This retrospective case\u2013control study evaluated patients who underwent MMS for removal of a basal or squamous cell carcinoma with same-day repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes and Measures:<\/jats:title>\n                    <jats:p>The primary endpoint was the incidence and comparison of postoperative morbidity. Risk for developing medical or cosmetic sequelae was determined through multivariate logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study population consisted of 143 propensity score-matched pairs (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009286) with moderate- to high-risk defects on the face, head, and neck. Compared with autologous tissue, placental allograft cases were associated with significantly lower risk for infection (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.004), poor scar cosmesis (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), scar revision (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001), or reoperation (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance:<\/jats:title>\n                    <jats:p>Postoperative complication rates for placental reconstructions did not exceed those demonstrated by autologous tissue counterparts, indicating this is a safe alternative to flap and FTSG in cosmetically sensitive repairs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/fpsam.2021.0167","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T09:16:31Z","timestamp":1635498991000},"page":"48-53","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Mohs Defect Repair with Dehydrated Human Amnion\/Chorion Membrane"],"prefix":"10.1177","volume":"24","author":[{"given":"Julia","family":"Toman","sequence":"first","affiliation":[{"name":"Division of Facial Plastics and Reconstructive Surgery, Department of Otolaryngology Head and Neck Surgery, University of South Florida, Tampa, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1797-9839","authenticated-orcid":false,"given":"Georgina M.","family":"Michael","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, MiMedx Group, Inc., Marietta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver J.","family":"Wisco","sequence":"additional","affiliation":[{"name":"Dermatology Health Specialists, Bend, Oregon, USA."},{"name":"Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Adams","sequence":"additional","affiliation":[{"name":"Advanced Dermatology and Skin Cancer Center, Manhattan, Kansas, USA."},{"name":"Division of Dermatology, Department of Internal Medicine, University of Kansas School of Medicine, Wichita, Kansas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon S.","family":"Hubbs","sequence":"additional","affiliation":[{"name":"Biostatistics Consulting, Alpharetta, GA, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,1,3]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21551"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20175701"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14202"},{"issue":"4","key":"e_1_3_6_5_2","first-page":"20","article-title":"The incidence of nonmelanoma skin cancers and acitinic keratoses in South Florida","volume":"5","author":"Nestor MS","year":"2012","unstructured":"Nestor MS, , Zarraga MB. The incidence of nonmelanoma skin cancers and acitinic keratoses in South Florida. J Clin Aesthet Dermatol. 2012; 5(4):20\u201324.","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1312691"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005074"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000005137"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.11124\/JBISRIR-2016-002997"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1584821"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.2310\/7750.2013.13188"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2019.02.003"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/1203475415586665"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3182a2e9eb"},{"key":"e_1_3_6_15_2","author":"Schwartzman G","unstructured":"Schwartzman G, , Carton AM, , Khachemoune A. Review and appraisal of assessment parameters of second intention healing after Mohs micrographic surgery. Arch Dermatol Res. [Epub ahead of print]; 10.1007\/s00403-021-02209-y.","journal-title":"Arch Dermatol Res"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamafacial.2016.0363"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2009.03.019"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2018.01.004"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000253"},{"key":"e_1_3_6_20_2","author":"Niknejad H","unstructured":"Niknejad H, , Peirovi H, , Jorjani M, , Ahmadiani A, , Ghanavi J, , Seifalian A. Properties of the amniotic membrane for potential use in tissue engineering. 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