{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:29:27Z","timestamp":1777660167871,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genetic Testing and Molecular Biomarkers"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1089\/gtmb.2010.0133","type":"journal-article","created":{"date-parts":[[2011,4,21]],"date-time":"2011-04-21T23:49:40Z","timestamp":1303429780000},"page":"415-421","source":"Crossref","is-referenced-by-count":4,"title":["High-Resolution Melting Analysis Is a More Effective Approach for Screening\n                    <i>TSC<\/i>\n                    Genes Mutations"],"prefix":"10.1177","volume":"15","author":[{"given":"Tz-Shiu","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mu-Yi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Tsui","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuan-Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ju-Li","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics and Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital, Lin-Kou, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Cheng","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuan-Pei","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Feng","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Chang Gung Memorial Hospital, Lin-Kou, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Shun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Ming","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Cheng","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Da-Chang","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Tao-Yuan, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e31803068c7"},{"key":"B2","first-page":"81","volume":"1","author":"Bourneville DM","year":"1880","journal-title":"Arch Neurol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.2008.00496.x"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1309\/BF3M-LJN8-J527-MWQY"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61279-9"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1086\/316951"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10159"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90618-Z"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90416-8"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1159\/000254569"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1042\/BST0370217"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-7-72"},{"key":"B13","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/clinchem\/45.8.1133","volume":"45","author":"Jones AC","year":"1999","journal-title":"Clin Chem"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s004390050040"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1086\/302381"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(07)70411-4"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/ng0992-37"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-001-0903-7"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2009.28"},{"key":"B20","first-page":"319","volume":"34","author":"Liou JD","year":"2004","journal-title":"Ann Clin Lab Sci"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1159\/000254570"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(199911)14:5<412::AID-HUMU7>3.0.CO;2-K"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1089\/gte.2007.0096"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1042\/BST0370433"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/6.9.1409"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5327.805"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(20000117)90:2<123::AID-AJMG7>3.0.CO;2-L"},{"key":"B28","first-page":"10","author":"Yu B","year":"2006","journal-title":"Curr Protoc Hum Genet Chapter 7:Unit7"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/s100380050185"}],"container-title":["Genetic Testing and Molecular Biomarkers"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/gtmb.2010.0133","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/gtmb.2010.0133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:21:44Z","timestamp":1777447304000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/gtmb.2010.0133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["10.1089\/gtmb.2010.0133"],"URL":"https:\/\/doi.org\/10.1089\/gtmb.2010.0133","relation":{},"ISSN":["1945-0265","1945-0257"],"issn-type":[{"value":"1945-0265","type":"print"},{"value":"1945-0257","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}