{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T19:55:38Z","timestamp":1784318138698,"version":"3.55.0"},"reference-count":37,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["High Altitude Medicine &amp; Biology"],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:p>\n                    H\u00fcfner, Katharina, Fabio Caramazza, Evelyn R. Pircher N\u00f6ckler, Agnieszka E. Stawinoga, Paolo Fusar-Poli, Sanjeeb S. Bhandari, Buddha Basnyat, Monika Brodmann Maeder, Giacomo Strapazzon, Iztok Tomazin, Ken Zafren, Hermann Brugger, and Barbara Sperner-Unterweger. Association of pre-existing mental health conditions with acute mountain sickness at Everest Base Camp.\n                    <jats:italic toggle=\"yes\">High Alt Med Biol.<\/jats:italic>\n                    23:338\u2013344, 2022.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Mental health disorders are common, but limited data are available regarding the number of people with a past medical history of psychiatric diagnoses going to high altitude (HA). It is also unknown whether mental health conditions are associated with an increased risk of acute mountain sickness (AMS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We analyzed data from a previous study at Everest Base Camp. Participants self-reported their past medical history and history of substance use and had a brief history taken by a physician. AMS was assessed using the self-reported 2018 Lake Louise AMS Score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Eighty-five participants (66 men and 19 women, age 38\u2009\u00b1\u20099 years) were included. When questioned by a physician, 28 participants reported prior diagnoses or symptoms compatible with depression (23%), anxiety disorder (6%), post-traumatic stress disorder (1%), and psychosis\/psychotic experiences (9%). The prevalence of psychiatric diagnoses in the past medical history was much lower in the self-reported data (2\/85) compared to data obtained via physician assessment (28\/85). Increased risks of AMS were associated with a past medical history of anxiety disorder (odds ratio [OR] 22.7; confidence interval [95% CI] 2.3\u2013220.6;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), depression (OR 3.6; 95% CI 1.2\u201311.2;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.022), and recreational drug use ever (OR 7.3; 95% CI 1.5\u201335.5;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Many people who travel to HA have a past medical history of mental health conditions. These individuals have an increased risk of scoring positive for AMS on the Lake Louise Score compared with people without a history of mental health conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/ham.2022.0014","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T16:02:48Z","timestamp":1662566568000},"page":"338-344","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Association of Pre-existing Mental Health Conditions with Acute Mountain Sickness at Everest Base Camp"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5453-8792","authenticated-orcid":false,"given":"Katharina","family":"H\u00fcfner","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital of Psychiatry II, Innsbruck Medical University, Innsbruck, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Caramazza","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital of Psychiatry II, Innsbruck Medical University, Innsbruck, Austria."},{"name":"Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy."},{"name":"Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn R.","family":"Pircher N\u00f6ckler","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital of Psychiatry II, Innsbruck Medical University, Innsbruck, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka E.","family":"Stawinoga","sequence":"additional","affiliation":[{"name":"Management and Committees, Eurac Research, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Fusar-Poli","sequence":"additional","affiliation":[{"name":"Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, United Kingdom."},{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeeb S.","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Mountain Medicine Society of Nepal, Kathmandu, Nepal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Buddha","family":"Basnyat","sequence":"additional","affiliation":[{"name":"Mountain Medicine Society of Nepal, Kathmandu, Nepal."},{"name":"Oxford University Clinical Research Unit, Patan Academy of Health Science, Nepal International, Kathmandu, Nepal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5608-7887","authenticated-orcid":false,"given":"Monika","family":"Brodmann Maeder","sequence":"additional","affiliation":[{"name":"Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy."},{"name":"SIME Swiss Institute of Medical Education, Bern, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4402-8633","authenticated-orcid":false,"given":"Giacomo","family":"Strapazzon","sequence":"additional","affiliation":[{"name":"Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iztok","family":"Tomazin","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia."},{"name":"Mountain Rescue Association of Slovenia, Kranj, Slovenia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4928-840X","authenticated-orcid":false,"given":"Ken","family":"Zafren","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Stanford University Medical Center, Palo Alto, California, USA."},{"name":"Department of Emergency Medicine, Alaska Native Medical Center, Anchorage, Alaska, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2752-6929","authenticated-orcid":false,"given":"Hermann","family":"Brugger","sequence":"additional","affiliation":[{"name":"Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy."},{"name":"Department of Anaesthesiology and Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Sperner-Unterweger","sequence":"additional","affiliation":[{"name":"Department 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