{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:50:54Z","timestamp":1777661454349,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["High Altitude Medicine &amp; Biology"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:p>\n                    Fossati, Alexandre, and Aleid C. J. Ruijs. Changes in fingertip cold-induced vasodilatation (hunting reaction) on acute exposure to altitude.\n                    <jats:italic toggle=\"yes\">High Alt Med Biol<\/jats:italic>\n                    . 25:212\u2013217, 2024.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Cold-induced vasodilation (CIVD) of the extremities is an interesting part of human physiology. Although the physiology of the CIVD reaction remains unknown, there are indications that hypoxia influences our CIVD reaction. The objective of this study is to measure the influence of acute hypoxia on the CIVD reaction of the fingertips.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      The CIVD reaction was measured using immersion of one hand in a water bath of 0\u00b0C in 12 healthy volunteers at low (1,235 m) and high (3,800 m) altitude during 35 minutes. High altitude was reached by a 20-minute cable car ride. Testing was performed indoors (room temperature, 22\u201325\u00b0C) at both altitudes. Data analysis was performed measuring the parameters of the CIVD reaction. Differences were found using the paired Student\u2019s\n                      <jats:italic toggle=\"yes\">t-test<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There was no significant difference in baseline finger temperature, onset time, peak time, and frequency of the CIVD reaction. However, at high altitude, maximum temperature and amplitude were significantly higher, slope was steeper, and minimum temperature was lower.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We did not find evidence for a diminished CIVD reaction at high altitude due to hypoxia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/ham.2023.0106","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T04:00:38Z","timestamp":1715572838000},"page":"212-217","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Changes in Fingertip Cold-Induced Vasodilatation (Hunting Reaction) on Acute Exposure to Altitude"],"prefix":"10.1177","volume":"25","author":[{"given":"Alexandre","family":"Fossati","sequence":"first","affiliation":[{"name":"D\u00e9partement de Chirurgie Orthop\u00e9dique, Centre Hospitalier Wallonie Picardie CHWAPI, Tournai, Belgium."},{"name":"D\u00e9partement de Chirurgie Orthop\u00e9dique, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4247-9000","authenticated-orcid":false,"given":"Aleid C. 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