{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:28:02Z","timestamp":1777681682632,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Health Security"],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:p>The National Emerging Special Pathogens Training and Education Center (NETEC) was established in 2015 to improve the capabilities of healthcare facilities to provide safe and effective care to patients with Ebola and other special pathogens in the United States. Through NETEC, a collaborative network of 10 Regional Emerging Special Pathogen Treatment Centers (RESPTCs) undertook readiness activities that included potential respiratory pathogens. These preparations, which took place before the COVID-19 pandemic, established a foundation of readiness that enabled RESPTCs to play a pivotal role in the US COVID-19 pandemic response. As initial COVID-19 cases were detected in the United States, RESPTCs provided essential isolation capacity, supplies, and subject matter expertise that allowed for additional time for healthcare systems to prepare. Through the Special Pathogen Research Network, RESPTCs rapidly enrolled patients into early clinical trials. During periods of high community transmission, RESPTCs provided educational, clinical, and logistical support to a wide range of healthcare and nonhealthcare settings. In this article, we describe how NETEC and the RESPTC network leveraged this foundation of special pathogen readiness to strengthen the national healthcare system's response to the COVID-19 pandemic. NETEC and the RESPTC network have proven to be an effective model that can support the national response to future emerging special pathogens.<\/jats:p>","DOI":"10.1089\/hs.2021.0188","type":"journal-article","created":{"date-parts":[[2022,4,28]],"date-time":"2022-04-28T16:58:39Z","timestamp":1651165119000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Contributions of the Regional Emerging Special Pathogen Treatment Centers to the US COVID-19 Pandemic Response"],"prefix":"10.1177","volume":"20","author":[{"given":"Jonathan D.","family":"Grein","sequence":"first","affiliation":[{"name":"Jonathan D. Grein, MD, is Director, both in Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer A.","family":"Garland","sequence":"additional","affiliation":[{"name":"Jennifer A. Garland, RN-BC, PhD, CIC, is Special Pathogens Clinical Program Manager, both in Hospital Epidemiology, Cedars-Sinai Medical Center, Los Angeles, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christa","family":"Arguinchona","sequence":"additional","affiliation":[{"name":"Christa Arguinchona, MSN, RN, CCRN, is Manager, Special Pathogens\/Infection Prevention, Providence Sacred Heart Medical Center, Spokane, WA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria G.","family":"Frank","sequence":"additional","affiliation":[{"name":"Maria G. Frank, MD, is a Hospitalist, Division of Hospital Medicine, Denver Health and Hospital Authority, and an Associate Professor of Medicine, School of Medicine, University of Colorado; both in Denver, CO."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian T.","family":"Garibaldi","sequence":"additional","affiliation":[{"name":"Brian T. Garibaldi, MD, MEHP, is Director, Johns Hopkins Biocontainment Unit, Johns Hopkins University School of Medicine, Baltimore, MD."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Grindle","sequence":"additional","affiliation":[{"name":"Amanda Grindle, RN, MSN, CNL, CPN, CCRN, is Clinical Program Manager, Special Care Unit, Children's Healthcare of Atlanta, Atlanta, GA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Hewlett","sequence":"additional","affiliation":[{"name":"Angela Hewlett, MD, MS, is an Associate Professor, Division of Infectious Diseases, Department of Internal Medicine; the George W. Orr MD and Linda Orr Chair in Health Security; and Medical Director, Nebraska Biocontainment Unit; all at the University of Nebraska Medical Center, Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Kline","sequence":"additional","affiliation":[{"name":"Susan Kline, MD, MPH, is Executive Medical Director for Infection Prevention, University of Minnesota Medical Center, and a Professor of Medicine, Division of Infectious Diseases and International Medicine, University of Minnesota Medical School; both in Minneapolis, MN."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corri B.","family":"Levine","sequence":"additional","affiliation":[{"name":"Corri B. Levine, PhD, MS, MPH, is Program Manager for Emerging and Special Pathogens Program, University of Texas Medical Branch, Galveston, TX."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneesh","family":"Mehta","sequence":"additional","affiliation":[{"name":"Aneesh Mehta, MD, is an Associate Professor of Medicine, Emory University School of Medicine, Atlanta, GA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikramjit","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Vikramjit Mukherjee, MD, FRCP(Edin), is an Assistant Professor, NYU School of Medicine; and is Director, Medical Intensive Care Unit, and Director, Special Pathogens Program, Bellevue Hospital Center; all in New York, NY."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren M.","family":"Sauer","sequence":"additional","affiliation":[{"name":"Lauren M. Sauer, MS, is Director, Special Pathogens Research Network, and is an Associate Professor, Department of Environmental, Agricultural, and Occupational Health, College of Public Health, Global Center for Health Security; both at the University of Nebraska Medical Center, Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen F.","family":"Searle","sequence":"additional","affiliation":[{"name":"Eileen F. Searle, PhD, RN, CCRN, is Biothreats Program Director, Center for Disaster Medicine, Massachusetts General Hospital, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Vanairsdale","sequence":"additional","affiliation":[{"name":"Sharon Vanairsdale, DNP, APRN, ACNS-BC, NP-C, CEN, FAEN, FAAN, is an Associate Professor, Clinical Track, Nell Hodgson Woodruff School of Nursing, Emory University; Program Director for Serious Communicable Diseases, Emory University Hospital; and Director of Education and Resources, National Emerging Special Pathogens Training and Education Center, Emory University; all in Atlanta, GA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Vasa","sequence":"additional","affiliation":[{"name":"Angela Vasa, MSN, RN, is Director of Isolation and Quarantine Services and Director, Readiness Consultations and Metrics Development, National Emerging Special Pathogens Training and Education Center; both at Nebraska Medicine, Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2017.0005"},{"key":"e_1_3_2_3_2","unstructured":"National Ebola Training and Education Center (NETEC). Annual Report FY2017. NETEC; 2018. Accessed February25 2022. https:\/\/netec.org\/wp-content\/uploads\/2018\/01\/NETEC-AR-2017.pdf"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2018.0106"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2017.0003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz616"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/ina.12506"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2020.451"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2018.0090"},{"key":"e_1_3_2_10_2","unstructured":"US Department of Health and Human Services Office of the Assistant Secretary of Preparedness and Response. 2018. Tranquil Terminus Full-Scale Exercise After Action Report. July 2018."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2018.0100"},{"key":"e_1_3_2_12_2","unstructured":"Cedars-Sinai. Cedars-Sinai Special Pathogens Symposium. 2019. Accessed March23 2022. https:\/\/cedars.cloud-cme.com\/course\/courseoverview?P=5&EID=8229"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6908e1"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0877-5"},{"key":"e_1_3_2_15_2","unstructured":"National Emerging Special Pathogens Training and Education Center. Accessed February25 2022. https:\/\/netec.org\/"},{"key":"e_1_3_2_16_2","unstructured":"National Emerging Special Pathogens Training and Education Center. YouTube Channel. https:\/\/www.youtube.com\/c\/TheNETEC\/videos"},{"key":"e_1_3_2_17_2","unstructured":"Lowe JJ Paladino KD Farke JD et al. N95 Filtering Facemask Receptor Ultraviolet Germicidal Irradiation (UVGI) Process for Decontamination and Reuse. Omaha: Nebraska Medicine; 2020. Accessed October7 2021. https:\/\/www.nebraskamed.com\/sites\/default\/files\/documents\/covid-19\/n-95-decon-process.pdf"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40506-021-00247-8"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/1535676020924171"},{"key":"e_1_3_2_20_2","unstructured":"Children's Healthcare of Atlanta. National Institutes of Health (NIH) awards $31 million to Children's Healthcare of Atlanta Emory University School of Medicine and Georgia Institute of Technology. Published May 28 2020. Accessed October7 2021. https:\/\/www.choa.org\/about-us\/newsroom\/nih-awards-31-million-to-childrens-emory-and-georgia-tech"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2020.435"},{"key":"e_1_3_2_22_2","unstructured":"Cohn M. Johns Hopkins doctor on Trump's coronavirus treatment team has plenty of experience treating contagious diseases. The Baltimore Sun. October 7 2020. Accessed February6 2022. https:\/\/www.baltimoresun.com\/coronavirus\/bs-hs-hopkins-doc-treats-trump-20201007-2lalexfg4jhktlrbmo3os4v2xm-story.html"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2021.2114"},{"key":"e_1_3_2_24_2","unstructured":"University of Nebraska Medical Center (UNMC). Global Center for Health Security Annual Report 2020. Omaha: UNMC; 2020. Accessed October5 2021. https:\/\/www.unmc.edu\/healthsecurity\/_documents\/GCHS-2020-Annual-Report.pdf"},{"key":"e_1_3_2_25_2","article-title":"Physician executives guide a successful Covid-19 response in Colorado","author":"Valin JP","year":"2020","unstructured":"Valin JP, , Gulley S, , Keidan B, et al. Physician executives guide a successful Covid-19 response in Colorado. NEJM Catalyst. October 15, 2020. doi:10.1056\/CAT.20.0402","journal-title":"NEJM Catalyst"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2007764"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2031994"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab376"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.108863"},{"key":"e_1_3_2_30_2","article-title":"The size and culturability of patient-generated SARS-CoV-2 aerosol","author":"Santarpia JL","year":"2021","unstructured":"Santarpia JL, , Herrera VL, , Rivera DN, et al. The size and culturability of patient-generated SARS-CoV-2 aerosol. J Expo Sci Environ Epidemiol. August 18, 2021. doi:10.1038\/s41370-021-00376-8","journal-title":"J Expo Sci Environ Epidemiol"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-70939-6"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.07.033"},{"key":"e_1_3_2_33_2","unstructured":"Johns Hopkins Institute for Clinical and Translational Research. COVID-19 Precision Medicine Analytics Platform Registry (JH-CROWN). Accessed March24 2022. https:\/\/ictr.johnshopkins.edu\/coronavirus\/jh-crown\/"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.3071"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa598"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.7326\/M20-6754"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.7326\/M20-3905"},{"key":"e_1_3_2_38_2","unstructured":"US Centers for Disease Control and Prevention. History of Ebola virus disease (EVD) outbreaks. Page last reviewed February 22 2022. Accessed March24 2022. https:\/\/www.cdc.gov\/vhf\/ebola\/history\/chronology.html"},{"key":"e_1_3_2_39_2","unstructured":"World Health Organization. Marburg virus disease \u2013 Guinea. Published September 17 2021. Accessed October5 2021. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/marburg-virus-disease---guinea"},{"key":"e_1_3_2_40_2","unstructured":"World Health Organization. Middle East respiratory syndrome coronavirus (MERS-CoV) \u2013 Saudi Arabia. Published August 17 2021. Accessed October5 2021. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/2021-DON333"},{"key":"e_1_3_2_41_2","unstructured":"World Health Organization. Nipah virus disease \u2013 India. Published September 24 2021. Accessed October5 2021. https:\/\/www.who.int\/emergencies\/disease-outbreak-news\/item\/nipah-virus-disease---india"},{"key":"e_1_3_2_42_2","unstructured":"US Centers for Disease Control and Prevention. Monkeypox in the United States. Page last reviewed November 17 2021. Accessed February25 2022. https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/2021-US-travel-case.html"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17239096"}],"container-title":["Health Security"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/hs.2021.0188","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/hs.2021.0188","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/hs.2021.0188","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:40:39Z","timestamp":1777452039000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/hs.2021.0188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,31]]},"references-count":42,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2022,6,1]]}},"alternative-id":["10.1089\/hs.2021.0188"],"URL":"https:\/\/doi.org\/10.1089\/hs.2021.0188","relation":{},"ISSN":["2326-5094","2326-5108"],"issn-type":[{"value":"2326-5094","type":"print"},{"value":"2326-5108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,31]]}}}