{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:28:02Z","timestamp":1777681682163,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T00:00:00Z","timestamp":1653955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Health Security"],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:p>Infectious disease outbreaks and pandemics have repeatedly threatened public health and have severely strained healthcare delivery systems throughout the past century. Pathogens causing respiratory illness, such as influenza viruses and coronaviruses, as well as the highly communicable viral hemorrhagic fevers, pose a large threat to the healthcare delivery system in the United States and worldwide. Through the Hospital Preparedness Program, within the US Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response, a nationwide Regional Ebola Treatment Network (RETN) was developed, building upon a state- and jurisdiction-based tiered hospital approach. This network, spearheaded by the National Emerging Special Pathogens Training and Education Center, developed a conceptual framework and plan for the evolution of the RETN into the National Special Pathogen System of Care (NSPS). Building the NSPS strategy involved reviewing the literature and the initial framework used in forming the RETN and conducting an extensive stakeholder engagement process to identify gaps and develop solutions. From this, the NSPS strategy and implementation plan were formed. The resulting NSPS strategy is an ambitious but critical effort that will have impacts on the mitigation efforts of special pathogen threats for years to come.<\/jats:p>","DOI":"10.1089\/hs.2022.0026","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T09:18:07Z","timestamp":1652951887000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["The Evolution of the National Special Pathogen System of Care"],"prefix":"10.1177","volume":"20","author":[{"given":"Vikramjit","family":"Mukherjee","sequence":"first","affiliation":[{"name":"Vikramjit Mukherjee, MD, FRCP (Edin), is Director, Medical ICU, NYC Health + Hospitals\/Bellevue, and an Assistant Professor of Medicine, NYU Grossman School of Medicine, New York, NY."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren M.","family":"Sauer","sequence":"additional","affiliation":[{"name":"Lauren M. Sauer, MSc, is Director, Special Pathogens Research Network, Global Center for Health Security, and an Associate Professor, Department of Environmental, Agricultural, and Occupational Health, College of Public Health, University of Nebraska Medical Center (UNMC); Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aneesh K.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Aneesh K. Mehta, MD, is a Professor, Division of Infectious Diseases, and Co-Principal Investigator, NETEC, Emory University School of Medicine, Atlanta, GA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia Y.","family":"Shea","sequence":"additional","affiliation":[{"name":"Sophia Y. Shea, MPH, is a Project Manager II, Global Center for Health Security, UNMC; Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Biddinger","sequence":"additional","affiliation":[{"name":"Paul D. Biddinger, MD, FACEP, is Chief Preparedness and Continuity Officer, Mass General Brigham; Director, Center for Disaster Medicine, Department of Emergency Medicine, Massachusetts General Hospital; and Associate Professor of Emergency Medicine, Harvard Medical School, Boston, MA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendan G.","family":"Carr","sequence":"additional","affiliation":[{"name":"Brendan G. Carr, MD, MS, is Chair and a Professor, Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura E.","family":"Evans","sequence":"additional","affiliation":[{"name":"Laura E. Evans, MD, MSc, is a Professor, Pulmonary, Critical and Sleep Medicine, University of Washington Medical Center, Seattle, WA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelly","family":"Schwedhelm","sequence":"additional","affiliation":[{"name":"Shelly Schwedhelm, MSN, RN, NEA-BC, is Executive Director, Emergency Management and Biopreparedness, Nebraska Medicine, and Executive Director, Emergency Management and Clinical Operations, Global Center for Health Security, UNMC; Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John J.","family":"Lowe","sequence":"additional","affiliation":[{"name":"John J. Lowe, PhD, is Co-Principal Investigator, National Emerging Special Pathogens Training and Education Center (NETEC), a Professor, Department of Environmental, Agricultural, and Occupational Health, College of Public Health, and Assistant Vice Chancellor for Health Security Training and Education, UNMC; Omaha, NE."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,31]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"World Health Organization. Severe acute respiratory syndrome (SARS). Accessed February8 2022. https:\/\/www.who.int\/health-topics\/severe-acute-respiratory-syndrome#tab=tab_1"},{"key":"e_1_3_2_3_2","unstructured":"US Centers for Disease Control and Prevention. SARS basics fact sheet. Page last reviewed December 6 2017. 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