{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T12:40:00Z","timestamp":1790167200194,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Health Security"],"published-print":{"date-parts":[[2025,2,1]]},"abstract":"<jats:p>From influenza to COVID-19, emerging infectious diseases have taken a heavy toll on lives and resources. Emerging infectious diseases represent one of the largest threats to national security. The primary mission of the Center for Biomedical Advanced Research and Development Authority (BARDA), within the US Administration for Strategic Preparedness and Response, is to support the advanced development of medical countermeasures (MCMs) for public health security threats, including select infectious diseases. Given the number of potential emerging infectious diseases, it is not feasible to develop a suite of MCMs necessary for a full response, including vaccines, therapeutics, and diagnostics. In this article, the authors describe BARDA\u2019s 3-step strategy to address emerging infectious diseases: (1) prioritize the development of MCMs for BARDA\u2019s priority pathogens with an increased focus on \u201cplatform technologies\u201d with rapid development capabilities; (2) develop response capabilities including specific licensed medical countermeasures and flexible, rapid MCM development infrastructure; and (3) improve those response capabilities, so they are finely tuned and ready when needed.<\/jats:p>","DOI":"10.1089\/hs.2024.0074","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T06:31:06Z","timestamp":1736922666000},"page":"55-61","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Building a Fast Response Capability for Emerging Infectious Diseases Within the Biomedical Advanced Research and Development Authority"],"prefix":"10.1177","volume":"23","author":[{"given":"Robert A.","family":"Johnson","sequence":"first","affiliation":[{"name":"Robert A. Johnson, PhD, is Director, Medical Countermeasures Programs, and Gary L. Disbrow, PhD, is Director, Center for Biomedical Advanced Research and Development Authority (BARDA), Washington, DC. Terence M. Barnhart, PhD, is Senior Strategy Implementation Leader, Tunnell Government Services, Inc. (Contractor Supporting BARDA), Washington, DC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5732-1189","authenticated-orcid":false,"given":"Terence M.","family":"Barnhart","sequence":"additional","affiliation":[{"name":"Robert A. Johnson, PhD, is Director, Medical Countermeasures Programs, and Gary L. Disbrow, PhD, is Director, Center for Biomedical Advanced Research and Development Authority (BARDA), Washington, DC. Terence M. Barnhart, PhD, is Senior Strategy Implementation Leader, Tunnell Government Services, Inc. (Contractor Supporting BARDA), Washington, DC."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary L.","family":"Disbrow","sequence":"additional","affiliation":[{"name":"Robert A. Johnson, PhD, is Director, Medical Countermeasures Programs, and Gary L. Disbrow, PhD, is Director, Center for Biomedical Advanced Research and Development Authority (BARDA), Washington, DC. Terence M. Barnhart, PhD, is Senior Strategy Implementation Leader, Tunnell Government Services, Inc. (Contractor Supporting BARDA), Washington, DC."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"ASPR. Public Health Emergency Medical Countermeasures Enterprise: Strategy and Implementation Plan 2022","year":"2022","unstructured":"Administration for Strategic Preparedness and Response (ASPR). Appendix B: PHEMCE high-priority threats. In: ASPR. Public Health Emergency Medical Countermeasures Enterprise: Strategy and Implementation Plan 2022. Washington, DC: ASPR; 2022. Accessed July 24, 2024. https:\/\/aspr.hhs.gov\/PHEMCE\/2022-SIP\/Pages\/Appendix-B-PHEMCE-High-Priority-Threats.aspx"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2022.2129930"},{"key":"e_1_3_2_4_2","unstructured":"Departments of Labor Health and Human Services and Education and Related Agencies Appropriation Bill 2024. S Rep 118-84. July 27 2023. Accessed September 26 2024. https:\/\/www.govinfo.gov\/content\/pkg\/CRPT-118srpt84\/html\/CRPT-118srpt84.htm"},{"key":"e_1_3_2_5_2","unstructured":"Division \u2013 Departments of Labor Health and Human Services and Education and Related Agencies Appropriations Act 2024. Explanatory statement. 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Accessed November 2 2023. https:\/\/medicalcountermeasures.gov\/barda\/fdaapprovals\/"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06536"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2021.1886931"},{"key":"e_1_3_2_11_2","unstructured":"US Department of Health and Human Services (HHS). Pandemic Influenza Plan: 2017 Update. Washington DC: HHS; 2017. Accessed July 24 2024. https:\/\/www.cdc.gov\/pandemic-flu\/media\/pan-flu-report-2017v2.pdf"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb2507"},{"key":"e_1_3_2_13_2","unstructured":"Hamel L Lopes L Kearney A Sparks G Stokes M Brody M. KFF COVID-19 Vaccine Monitor: June 2021. Kaiser Family Foundation. Published June 30 2021. Accessed September 26 2024. https:\/\/www.kff.org\/coronavirus-covid-19\/poll-finding\/kff-covid-19-vaccine-monitor-june-2021\/"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163339"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.8121"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-14-469"},{"key":"e_1_3_2_17_2","author":"National Academies of Sciences, Engineering, and Medicine","year":"2016","unstructured":"National Academies of Sciences, Engineering, and Medicine. Rapid Medical Countermeasure Response to Infectious Diseases: Enabling Sustainable Capabilities Through Ongoing Public- and Private-Sector Partnerships: Workshop Summary. Washington, DC: The National Academies Press; 2016. 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