{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T21:12:50Z","timestamp":1777669970916,"version":"3.51.4"},"reference-count":55,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Gene Therapy"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1089\/hum.2010.121","type":"journal-article","created":{"date-parts":[[2010,12,14]],"date-time":"2010-12-14T09:33:33Z","timestamp":1292319213000},"page":"935-949","source":"Crossref","is-referenced-by-count":6,"title":["Recombinant Adeno-Associated Virus-Mediated Gene Transfer for the Potential Therapy of Adenosine Deaminase-Deficient Severe Combined Immune Deficiency"],"prefix":"10.1177","volume":"22","author":[{"given":"Jared N.","family":"Silver","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Elder","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Conlon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Cruz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"Wright","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Powell Gene Therapy Center, University of Florida College of Medicine, Gainesville, FL 32610."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terence R.","family":"Flotte","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01655."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1089\/104303401753153956"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2004.05.012"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31666"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e3281900f01"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2003.10.013"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.9.5093"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.24.14323"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2006.12.009"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32949"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2006.02.013"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30953"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000057858.45649.F7"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1186\/1423-0127-17-26"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00258.2005"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0903652"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.4.7.1093"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1126\/science.1091667"},{"key":"B18","doi-asserted-by":"crossref","first-page":"8568","DOI":"10.1128\/JVI.72.11.8568-8577.1998","volume":"72","author":"Duan D.","year":"1998","journal-title":"J. Virol."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000189226.03684.fe"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21173"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.22.10613"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.11.5.7946381"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1089\/1043034041361190"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1089\/hum.1996.7.9-1145"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.251532298"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2005.04.018"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1088547"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(03)00104-3"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198703053161005"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2006.03.014"},{"key":"B31","doi-asserted-by":"crossref","first-page":"293","DOI":"10.18388\/abp.2005_3442","volume":"52","author":"Kapturczak M.H.","year":"2005","journal-title":"Acta Biochim. Pol."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/73464"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.24.14082"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1122"},{"key":"B35","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1128\/CDLI.12.7.861-866.2005","volume":"12","author":"Lainka E.","year":"2005","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"B36","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1681\/ASN.V1091908","volume":"10","author":"Lipkowitz M.S.","year":"1999","journal-title":"J. Am. Soc. Nephrol."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2008.242"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1002\/jgm.896"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802315"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-10-3296"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1126\/science.294.5547.1640"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(95)01488-8"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2008.01.025"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-75608-5_5"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000237661.18885.f6"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mt.6300297"},{"key":"B47","first-page":"43","volume":"2","author":"Poirier A.","year":"2004","journal-title":"Preclinica"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.2174\/1566523054065066"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0307833100"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1006\/mthe.2002.0673"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00542-08"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2008.87"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.02220.x"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1089\/104303402760128577"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.08.066"}],"container-title":["Human Gene Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/hum.2010.121","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/hum.2010.121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:54:26Z","timestamp":1777449266000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/hum.2010.121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":55,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["10.1089\/hum.2010.121"],"URL":"https:\/\/doi.org\/10.1089\/hum.2010.121","relation":{},"ISSN":["1043-0342","1557-7422"],"issn-type":[{"value":"1043-0342","type":"print"},{"value":"1557-7422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8]]}}}