{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:16:36Z","timestamp":1789769796410,"version":"4.0.1"},"reference-count":51,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Gene Therapy"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1089\/hum.2017.133","type":"journal-article","created":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T02:04:04Z","timestamp":1514513044000},"page":"708-718","source":"Crossref","is-referenced-by-count":50,"title":["Long-Term Sustained Effect of Liver-Targeted Adeno-Associated Virus Gene Therapy for Mitochondrial Neurogastrointestinal Encephalomyopathy"],"prefix":"10.1177","volume":"29","author":[{"given":"Javier","family":"Torres-Torronteras","sequence":"first","affiliation":[{"name":"Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."},{"name":"Biomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Cabrera-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."},{"name":"Biomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Vila-Juli\u00e0","sequence":"additional","affiliation":[{"name":"Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."},{"name":"Biomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Viscomi","sequence":"additional","affiliation":[{"name":"MRC-Mitochondrial Biology Unit, MRC MBU, Wellcome Trust\/MRC Building, Hills Road, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"C\u00e1mara","sequence":"additional","affiliation":[{"name":"Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."},{"name":"Biomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michio","family":"Hirano","sequence":"additional","affiliation":[{"name":"H. Houston Merritt Center, Department of Neurology, Columbia University Medical Center, New York, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Zeviani","sequence":"additional","affiliation":[{"name":"MRC-Mitochondrial Biology Unit, MRC MBU, Wellcome Trust\/MRC Building, Hills Road, Cambridge, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Mart\u00ed","sequence":"additional","affiliation":[{"name":"Research Group on Neuromuscular and Mitochondrial Diseases, Vall d'Hebron Research Institute, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain."},{"name":"Biomedical Network Research Centre on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1086\/301979"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1097\/01.nrl.0000106919.06469.04"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.4.721"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(03)00294-8"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2003.128"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr245"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu068"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1002035"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M604498200"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C300401200"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2010.100"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv226"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000240853.97716.24"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2017.02.006"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24724"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddn401"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2011.24"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2015.160"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2014.6"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2007.06.042"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-09-2889"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2014.41"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1517\/21678707.2015.1090307"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.15.6969-6976.2001"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0676.2002.01702.x"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.05.044"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1407309"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2016.018"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2006.17.601"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2009.139"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2009.031"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2005.01.012"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2013.166"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096692"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/nature12875"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2016.61"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2015.206"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2015.174"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2015.179"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1126\/science.1142658"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3389"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2005.03.020"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-08-302729"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2016.52"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3230"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3584"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3578"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1172\/JCI79213"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200706015"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1177\/019262339602400606"}],"container-title":["Human Gene Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/hum.2017.133","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/hum.2017.133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:54:33Z","timestamp":1777449273000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/hum.2017.133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1089\/hum.2017.133"],"URL":"https:\/\/doi.org\/10.1089\/hum.2017.133","relation":{},"ISSN":["1043-0342","1557-7422"],"issn-type":[{"value":"1043-0342","type":"print"},{"value":"1557-7422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6]]}}}