{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:11:38Z","timestamp":1789020698251,"version":"build-2803163510"},"reference-count":46,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Gene Therapy"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1089\/hum.2017.163","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T15:05:21Z","timestamp":1510326321000},"page":"312-326","source":"Crossref","is-referenced-by-count":80,"title":["Adeno-Associated Virus Gene Therapy in a Sheep Model of Tay\u2013Sachs Disease"],"prefix":"10.1177","volume":"29","author":[{"given":"Heather L.","family":"Gray-Edwards","sequence":"first","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley N.","family":"Randle","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy A.","family":"Maitland","sequence":"additional","affiliation":[{"name":"Department of Neurology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector R.","family":"Benatti","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spencer M.","family":"Hubbard","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter F.","family":"Canning","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew B.","family":"Vogel","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon L.","family":"Brunson","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misako","family":"Hwang","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Ellis","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison M.","family":"Bradbury","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"},{"name":"Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atoska S.","family":"Gentry","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda R.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne A.","family":"Wooldridge","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewey R.","family":"Wilhite","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randolph L.","family":"Winter","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian K.","family":"Whitlock","sequence":"additional","affiliation":[{"name":"Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob A.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merilee","family":"Holland","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nouha","family":"Salibi","sequence":"additional","affiliation":[{"name":"MR R&D Siemens Healthcare, Malvern, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald J.","family":"Beyers","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Sartin","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas S.","family":"Denney","sequence":"additional","affiliation":[{"name":"Department of Electrical and Computer Engineering, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy R.","family":"Cox","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"},{"name":"Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Sena-Esteves","sequence":"additional","affiliation":[{"name":"Department of Neurology and Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas R.","family":"Martin","sequence":"additional","affiliation":[{"name":"Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, Alabama"},{"name":"Department of Anatomy, Physiology, and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.3.249"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-0078"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0588"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/5.1.1"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1126\/science.404709"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810388522"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2010.08.006"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/ng1095-170"},{"key":"B9","first-page":"7","author":"Rockwell HE","year":"2015","journal-title":"ASN Neuro"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2014.108"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.86"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2012.44"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2015.05.003"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0603765103"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2014.240"},{"key":"B16","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/mt.2013.86","volume":"21","author":"Bradbury AM","year":"2013","journal-title":"Mol Ther"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-2306-9_11"},{"key":"B18","doi-asserted-by":"crossref","first-page":"706","DOI":"10.2460\/ajvr.1997.58.07.706","volume":"58","author":"Steiss JE","year":"1997","journal-title":"Am J Vet Res"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2014.09.020"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1126\/science.1145206"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(88)50090-6"},{"key":"B22","first-page":"371","author":"Jasper HH","year":"1958","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3007733"},{"key":"B24","first-page":"434","volume":"19","author":"Lacorazza HD","year":"1995","journal-title":"Biotechniques"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(57)90254-8"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv026"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(74)90097-6"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2002.00765.x"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1202285"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-009-1450-z"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-005-1542-3"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.37468"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.6.737"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-003-0004-x"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv086"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410240314"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.203.3.9169712"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M306126200"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-007-0469-0"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2012.101"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2013.005"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-015-9223-1"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66778"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu727"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2015.189"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2014.135"}],"container-title":["Human Gene Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/hum.2017.163","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/hum.2017.163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T07:54:28Z","timestamp":1777449268000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/hum.2017.163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1089\/hum.2017.163"],"URL":"https:\/\/doi.org\/10.1089\/hum.2017.163","relation":{},"ISSN":["1043-0342","1557-7422"],"issn-type":[{"value":"1043-0342","type":"print"},{"value":"1557-7422","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}