{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:03:24Z","timestamp":1792440204422,"version":"4.5.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Gene Therapy Clinical Development"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1089\/humc.2017.249","type":"journal-article","created":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T13:08:28Z","timestamp":1522328908000},"page":"48-59","source":"Crossref","is-referenced-by-count":110,"title":["A Multicenter, Double-Blind, Phase III Clinical Trial to Evaluate the Efficacy and Safety of a Cell and Gene Therapy in Knee Osteoarthritis Patients"],"prefix":"10.1177","volume":"29","author":[{"given":"Myung-Ku","family":"Kim","sequence":"first","affiliation":[{"name":"Inha University Hospital, Incheon, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul-Won","family":"Ha","sequence":"additional","affiliation":[{"name":"Samsung Medical Center, Sung Kyun Kwan University School of Medicine, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"In","sequence":"additional","affiliation":[{"name":"The Catholic University of Korea College of Medicine, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Do","family":"Cho","sequence":"additional","affiliation":[{"name":"Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eui-Sung","family":"Choi","sequence":"additional","affiliation":[{"name":"Chungbuk National University Hospital, Cheongju, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Ku","family":"Ha","sequence":"additional","affiliation":[{"name":"Seoul Paik Hospital, Inje University, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Hong","family":"Lee","sequence":"additional","affiliation":[{"name":"Jeonbuk National University Medical School, Jeonju, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Doo","family":"Yoo","sequence":"additional","affiliation":[{"name":"Ewha Womans University Mokdong Hospital, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Il","family":"Bin","sequence":"additional","affiliation":[{"name":"Asan Medical Center, University of Ulsan College of Medicine, Ulsan, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choong-Hyeok","family":"Choi","sequence":"additional","affiliation":[{"name":"College of Medicine, Hanyang University, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Soo","family":"Kyung","sequence":"additional","affiliation":[{"name":"Kyungpook National University, Daegu, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung-Chul","family":"Lee","sequence":"additional","affiliation":[{"name":"Seoul National University Hospital, Seoul, South Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61729-2"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2013.05.069"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204763"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001388"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/ar148"},{"key":"B6","first-page":"279","volume":"71","author":"Van Beuningen HM","year":"1994","journal-title":"Lab Invest"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.153.1.35"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.02.005"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.03.003"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1002\/art.38614"},{"key":"B11","first-page":"445","volume":"34","author":"Dahlberg LE","year":"2016","journal-title":"Clin Exp Rheumatol"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-016-1085-9"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-011-1376-z"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200005000-00020"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2005.11.1516"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3109\/14653249.2011.629645"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1089\/humc.2014.145"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.97B7.35852"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/BF01560215"},{"key":"B20","doi-asserted-by":"crossref","first-page":"S240","DOI":"10.1002\/acr.20543","volume":"63","author":"Hawker GA","year":"2011","journal-title":"Arthritis Care Res"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.05.005"},{"key":"B23","first-page":"1833","volume":"15","author":"Bellamy N","year":"1988","journal-title":"J Rheumatol"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0838.1998.tb00465.x"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.05.012"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204052"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/68875123"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.02.010"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0181956"},{"key":"B31","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1136\/annrheumdis-2015-207602","volume":"75","author":"Hunter D","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2004.02.001"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1002\/art.39063"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-009-0905-y"},{"key":"B35","first-page":"31","volume":"12","author":"Migliore A","year":"2015","journal-title":"Clin Cases Miner Bone Metab"}],"container-title":["Human Gene Therapy Clinical Development"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/humc.2017.249","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/humc.2017.249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T03:59:23Z","timestamp":1772423963000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/humc.2017.249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1089\/humc.2017.249"],"URL":"https:\/\/doi.org\/10.1089\/humc.2017.249","relation":{},"ISSN":["2324-8637","2324-8645"],"issn-type":[{"value":"2324-8637","type":"print"},{"value":"2324-8645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}