{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:31:12Z","timestamp":1777908672721,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Aerosol Medicine and Pulmonary Drug Delivery"],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:p>Interruptions in continuous nebulized pulmonary vasodilators, such as epoprostenol, can potentially result in clinical deterioration in respiratory status. Coadministration of other intermittent nebulized therapies may require opening the ventilator circuit to facilitate administration. However, in patients with SARS-CoV2 infection, it is preferred to avoid opening the circuit whenever feasible to prevent aerosolization of the virus and exposure of health care workers. In this study, we describe a unique method of administering continuous epoprostenol nebulization and intermittent nebulized antibiotics, mucolytics, and bronchodilators, using Aerogen vibrating mesh nebulizers without interruptions in epoprostenol or opening the ventilator circuit. This technique set up consisted of stacking two Aerogen nebulizer cups, each with its own controller. This approach was successful in allowing concomitant delivery of intermittent and continuous nebulized therapy without interruptions. To our knowledge, this method has not been previously described in the literature and may be helpful to bedside clinicians facing a similar clinical scenario.<\/jats:p>","DOI":"10.1089\/jamp.2020.1636","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T09:46:16Z","timestamp":1598521576000},"page":"357-360","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Uninterrupted Continuous and Intermittent Nebulizer Therapy in a COVID-19 Patient Using Sequential Vibratory Mesh Nebulizers: A Case Report"],"prefix":"10.1177","volume":"33","author":[{"given":"Ola","family":"Elnadoury","sequence":"first","affiliation":[{"name":"Department of Pharmacy, NYU Langone Hospital\u2014Brooklyn, Brooklyn, New York, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Beattie","sequence":"additional","affiliation":[{"name":"Department of Medicine\u2014Pulmonary, Memorial Sloan Kettering Cancer Center, New York, New York, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony S.","family":"Lubinsky","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, NYU Langone Health, New York, New York, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,2]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.1585"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005372"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1901686"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1365"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0897190019830504"},{"key":"e_1_3_4_8_2","first-page":"288","article-title":"[Expert consensus on preventing nosocomial transmission during respiratory care for critically ill patients infected by 2019 Novel Coronavirus Pneumonia]","volume":"43","author":"Respiratory Care Committee of Chinese Thoracic Society","year":"2020","unstructured":"Respiratory Care Committee of Chinese Thoracic Society: [Expert consensus on preventing nosocomial transmission during respiratory care for critically ill patients infected by 2019 Novel Coronavirus Pneumonia]. Chin J Tubercul Respir Dis. 2020; 43:288\u2013296.","journal-title":"Chin J Tubercul Respir Dis"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2209"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31827515de"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1916-6"}],"container-title":["Journal of Aerosol Medicine and Pulmonary Drug Delivery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jamp.2020.1636","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jamp.2020.1636","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jamp.2020.1636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:10:55Z","timestamp":1777644655000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jamp.2020.1636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,12,1]]}},"alternative-id":["10.1089\/jamp.2020.1636"],"URL":"https:\/\/doi.org\/10.1089\/jamp.2020.1636","relation":{},"ISSN":["1941-2711","1941-2703"],"issn-type":[{"value":"1941-2711","type":"print"},{"value":"1941-2703","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,1]]}}}