{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:38:42Z","timestamp":1790908722081,"version":"4.1.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Aerosol Medicine and Pulmonary Drug Delivery"],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Chronic rhinosinusitis (CRS) is a disease that can significantly reduce patients' quality of life (QoL). Intranasal steroid therapy is the most commonly used treatment for CRS. There are many evaluation tools dedicated to assessing CRS patients' QoL, but none of them evaluates QoL during local steroid therapy. Mucosal atomization devices (MADs) and nasal saline irrigation (NSI) are effective and safe methods of applying intranasal steroids for CRS patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The sample population for this prospective study comprised 43 CRS patients. Following endoscopic sinus surgery, all participants received intranasal steroids administered via an MAD, followed by NSI for 1.5 months. Each participant completed the SNOT-22 (22-item Sino-Nasal Outcomes Test) score and a new questionnaire, the Complementary Topical Nasal Drug Delivery Questionnaire (the Complementary Questionnaire), at the end of 3 months of intranasal steroid therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The patients' responses in both the SNOT-22 score and the Complementary Questionnaire revealed significant differences in their adverse experiences. The patients who received intranasal steroid treatment using NSI experienced more frequently delayed nasal drainage, higher frequency of ear symptoms, and facial pain\/pressure, while those whose therapy was administered using an MAD reported complaints such as nasal irritation, nasal dryness, and postnasal drip with unpleasant taste\/smell.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>We used the Complementary Questionnaire as an effective tool for assessment of the QoL of CRS patients. The SNOT-22 score and the Complementary Questionnaire make it possible to select an intranasal applicator tailored to a CRS patient's specific complaints.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jamp.2020.1644","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T17:32:31Z","timestamp":1618335151000},"page":"311-321","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Intranasal Steroid Application Using Nasal Saline Irrigation and a Mucosal Atomization Device to Treat Chronic Rhinosinusitis"],"prefix":"10.1177","volume":"34","author":[{"given":"Martyna","family":"Waniewska-Leczycka","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Cieslik","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Kowalik","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Sierdzinski","sequence":"additional","affiliation":[{"name":"Medical Informatics and Telemedicine Department, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariola Popko","family":"Zagor","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"issue":"29","key":"e_1_3_3_2_2","first-page":"1","article-title":"European Position Paper on Rhinosinusitis and Nasal Polyps 2020","volume":"58","author":"Fokkens WJ","year":"2020","unstructured":"Fokkens WJ, , Lund VJ, , Hopkins C, , Hellings PW, , Kern R, , Reitsma S, , Toppila-Salmi S, , Bernal-Sprekelsen M, , Mullol J, , Alobid I, , Terezinha Anselmo-Lima W, , Bachert C, , Baroody F, , von Buchwald C, , Cervin A, , Cohen N, , Constantinidis J, , De Gabory L, , Desrosiers M, , Diamant Z, , Douglas RG, , Gevaert PH, , Hafner A, , Harvey RJ, , Joos GF, , Kalogjera L, , Knill A, , Kocks JH, , Landis BN, , Limpens J, , Lebeer S, , Lourenco O, , Meco C, , Matricardi PM, , O'Mahony L, , Philpott CM, , Ryan D, , Schlosser R, , Senior B, , Smith TL, , Teeling T, , Tomazic PV, , Wang DY, , Wang D, , Zhang L, , Agius AM, , Ahlstrom-Emanuelsson C, , Alabri R, , Albu S, , Alhabash S, , Aleksic A, , Aloulah M, , Al-Qudah M, , Alsaleh S, , Baban MA, , Baudoin T, , Balvers T, , Battaglia P, , Bedoya JD, , Beule A, , Bofares KM, , Braverman I, , Brozek-Madry E, , Richard B, , Callejas C, , Carrie S, , Caulley L, , Chussi D, , de Corso E, , Coste A, , El Hadi U, , Elfarouk A, , Eloy PH, , Farrokhi S, , Felisati G, , Ferrari MD, , Fishchuk R, , Grayson W, , Goncalves PM, , Grdinic B, , Grgic V, , Hamizan AW, , Heinichen JV, , Husain S, , Ping TI, , Ivaska J, , Jakimovska F, , Jovancevic L, , Kakande E, , Kamel R, , Karpischenko S, , Kariyawasam HH, , Kawauchi H, , Kjeldsen A, , Klimek L, , Krzeski A, , Kopacheva Barsova G, , Kim SW, , Lal D, , Letort JJ, , Lopatin A, , Mahdjoubi A, , Mesbahi A, , Netkovski J, , Nyenbue Tshipukane D, , Obando-Valverde A, , Okano M, , Onerci M, , Ong YK, , Orlandi R, , Otori N, , Ouennoughy K, , Ozkan M, , Peric A, , Plzak J, , Prokopakis E, , Prepageran N, , Psaltis A, , Pugin B, , Raftopulos M, , Rombaux P, , Riechelmann H, , Sahtout S, , Sarafoleanu CC, , Searyoh K, , Rhee CS, , Shi J, , Shkoukani M, , Shukuryan AK, , Sicak M, , Smyth D, , Snidvongs K, , Soklic Kosak T, , Stjarne P, , Sutikno B, , Steinsvag S, , Tantilipikorn P, , Thanaviratananich S, , Tran T, , Urbancic J, , Valiulius A, , Vasquez de Aparicio C, , Vicheva D, , Virkkula PM, , Vicente G, , Voegels R, , Wagenmann MM, , Wardani RS, , Welge-Lussen A, , Witterick I, , Wright E, , Zabolotniy D, , Zsolt B, , and Zwetsloot CP: European Position Paper on Rhinosinusitis and Nasal Polyps 2020. 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