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We present the case of a 29-year-old woman with a locally advanced cervical VC who underwent radiotherapy followed by radical hysterectomy. After local relapse and despite pelvic exenteration, her condition deteriorated. Treatment of choice in VC is surgery, because of the risk of anaplastic transformation under irradiation, raising the chances of distant spread and converting this rather benign-like type of cancer to an aggressive cancer.<\/jats:p>","DOI":"10.1089\/jayao.2017.0009","type":"journal-article","created":{"date-parts":[[2017,5,12]],"date-time":"2017-05-12T12:20:56Z","timestamp":1494591656000},"page":"499-502","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Good Prognosis Went Badly: Fulminant Evolution of a 29-Year-Old Patient with Verrucous Carcinoma of the Cervix"],"prefix":"10.1177","volume":"6","author":[{"given":"Rodica M.","family":"Anghel","sequence":"first","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]},{"name":"University of Medicine and Pharmacy \u201cCarol Davila","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oana G.","family":"Trifanescu","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]},{"name":"University of Medicine and Pharmacy \u201cCarol Davila","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu I.","family":"Mitrica","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]},{"name":"University of Medicine and Pharmacy \u201cCarol Davila","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiana G.","family":"Curea","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inga","family":"Botnariuc","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalin G.","family":"Herghelegiu","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila","place":["Romania"]},{"name":"\u201cAlfred Rusescu\u201d Institute for Mother and Child Care","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina M.","family":"Orlov","sequence":"additional","affiliation":[{"name":"Institute of Oncology \u201cProf. Dr. Alexandru Trestioreanu,\u201d","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia M.","family":"Ilie","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u201cCarol Davila","place":["Romania"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,5,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196601)19:1<26::AID-CNCR2820190103>3.0.CO;2-L"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.7874\/jao.2016.20.3.183"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1556\/OH.2011.29049"},{"issue":"6","key":"e_1_3_2_5_2","first-page":"4491","article-title":"Verrucous carcinoma of the cervix: detection of carcinogenetic human papillomavirus types and their role during follow-up","volume":"27","author":"Frega A","year":"2007","unstructured":"Frega A, , Lukic A, , Nobili F, et al. 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