{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:02:14Z","timestamp":1788883334066,"version":"build-2803163510"},"reference-count":25,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Several studies have indicated that dietary interventions may offer protection against the development of cardiac damage in the case of anthracycline-induced cardiomyopathy (AIC). The goal of this study was to assess whether an evidence-based cardioprotective diet can be effective in preventing AIC in patients with breast cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Randomized, open-label, controlled trial. The study period was set for 18 weeks, and the data were analyzed by generalized estimating equation modeling and one-way repeated measures analysis of variance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting\/Location:<\/jats:title>\n                    <jats:p>Shahid Rajaie Hospital affiliated (Tehran, Iran).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects:<\/jats:title>\n                    <jats:p>Fifty anthracycline-treated patients with breast cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions:<\/jats:title>\n                    <jats:p>Patients were randomized to receive either a 2-hour training in evidence-based cardio-protective diet or Carvedilol 6.25 mg bid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Outcome Measures:<\/jats:title>\n                    <jats:p>The primary outcome was the number of patients with abnormal left ventricular ejection fraction (LVEF) after 18 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At week 18, 12 (48%) out of 25 participants in the cardioprotective diet group had abnormal LVEF in comparison with 21 (84%) out of 25 in the carvedilol group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.007). Also, 2 (8%) out of 25 in the cardioprotective diet group compared with 7 (28%) out of 25 participants in the carvedilol group had abnormal global longitudinal strain (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.066). The diet group showed significant improvements in the quality-of-life dimensions named \u201chealth change\u201d and \u201cgeneral health\u201d compared with the carvedilol group using the Short Form-36 Health Survey questionnaire.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study suggests that an evidence-based cardioprotective diet can contribute to the prevention of AIC. Although current treatments for AIC can be effective, further research is mandatory for more options.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jicm.2023.0777","type":"journal-article","created":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T07:52:25Z","timestamp":1715932345000},"page":"995-1001","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Cardioprotective Diet to Prevent Anthracycline-Induced Cardiotoxicity in Patients with Breast Cancer: A Randomized Open-Label Controlled Trial"],"prefix":"10.1177","volume":"30","author":[{"given":"Azin","family":"Alizadehasl","sequence":"first","affiliation":[{"name":"Cardio-Oncology Research Center, Rajaie Cardiovascular Medical &amp; Research Center, Iran University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Malekzadeh Moghani","sequence":"additional","affiliation":[{"name":"Shohada-e Tajrish Hospital, Department of RadioOncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamidreza","family":"Mirzaei","sequence":"additional","affiliation":[{"name":"Shohada-e Tajrish Hospital, Department of RadioOncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran."},{"name":"Cancer Research Center, Shohadae Tajrish Hospital, Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masoumeh","family":"Keshvari","sequence":"additional","affiliation":[{"name":"Clinical Research Development Center, Mahdiyeh Educational Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Fadaei","sequence":"additional","affiliation":[{"name":"Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3640-8046","authenticated-orcid":false,"given":"Holger","family":"Cramer","sequence":"additional","affiliation":[{"name":"Institute for General Practice and Interprofessional Care, Tuebingen, University Hospital Tuebingen, Tuebingen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2458-2626","authenticated-orcid":false,"given":"Mehdi","family":"Pasalar","sequence":"additional","affiliation":[{"name":"Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-5918","authenticated-orcid":false,"given":"Ghazaleh","family":"Heydarirad","sequence":"additional","affiliation":[{"name":"Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20211033"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2020.00026"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.018585"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.7812\/tpp\/12-085"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1800389"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2016.02.078"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu13124324"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.4021\/jocmr2009.02.1225"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312103"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21319"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.968735"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12012-019-09558-1"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/jicm.2022.0624"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.013777"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jew223"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e328326291a"},{"issue":"6","key":"e_1_3_8_18_2","first-page":"61","article-title":"The effect of diet and exercise on improvement of quality of life in patients with nonalcoholic steatohepatitis","volume":"21","author":"Nikroo H","year":"2013","unstructured":"Nikroo H, , Mohammadian M, , Nematy M, et al. 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