{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T10:27:21Z","timestamp":1787135241025,"version":"build-2736575974"},"reference-count":55,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative and Complementary Medicine"],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To systematically assess the therapeutic impact of music interventions on hypertensive disorders of pregnancy (HDP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Systematic review and meta-analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A comprehensive search of various databases, such as PubMed, Embase, Cochrane Library, Web of Science, Scopus, CINAHL, EBSCO, Chinese National Knowledge Infrastructure, China Biomedical Literature Database, and Foreign Medical Literature Retrieval Service, was conducted to identify randomized controlled trials (RCTs) investigating the impact of music therapy on HDP from their inception through March 2024. Two independent reviewers performed study selection, data extraction, and risk-of-bias assessment using RoB 2. Statistical analyses were conducted in STATA 17, with evidence certainty graded using Grading of Recommendations Assessment, Development, and Evaluation. The protocol followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and was prospectively registered in PROSPERO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The meta-analysis included 14 RCTs comprising 1,477 participants. Five separate meta-analyses were conducted to compare the efficacy of music therapy versus standard care. Moderate-quality evidence from randomized trials demonstrated significant reductions associated with music therapy in systolic blood pressure (mean difference [MD]\n                      <jats:italic toggle=\"yes\">= \u2212<\/jats:italic>\n                      10.55 mmHg, 95% confidence interval [CI]: \u221213.86 to \u22127.24,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05), diastolic blood pressure (MD\n                      <jats:italic toggle=\"yes\">= \u2212<\/jats:italic>\n                      8.14 mmHg, 95% CI: \u221210.59 to \u22125.58,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05), sleep quality in patients with hypertension (MD\n                      <jats:italic toggle=\"yes\">= \u2212<\/jats:italic>\n                      1.95 points, 95% CI: \u22122.41 to \u22121.49,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05), and depression (MD\n                      <jats:italic toggle=\"yes\">= \u2212<\/jats:italic>\n                      7.80 points, 95% CI: \u22129.97 to \u22125.64,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). Low-quality evidence suggested a modest improvement in anxiety (MD\n                      <jats:italic toggle=\"yes\">= \u2212<\/jats:italic>\n                      7.24 points, 95% CI: \u22128.84 to \u22125.64,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05). No publication bias was found in the comprehensive analysis results (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &gt; 0.1).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our systematic review suggests that adjunctive music therapy provides clinically relevant benefits for controlling systolic and diastolic blood pressure and improving psychological outcomes including anxiety, depression, and sleep quality in patients with HDP when compared with standard care alone.<\/jats:p>\n                  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