{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:25:05Z","timestamp":1785381905671,"version":"3.55.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"7-8","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>\n                    The methanolic extracts of the leaves of\n                    <jats:italic toggle=\"yes\">Lippia<\/jats:italic>\n                    species (\n                    <jats:italic toggle=\"yes\">L. pseudo-thea, L. hermannioides, L. alba, L. rubella,<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">L. sidoides<\/jats:italic>\n                    ) were tested for their antibacterial, antifungal, and antioxidant activity. Cytotoxicity was determined by using brine shrimp lethality bioassay. Phytochemical screening was also performed. The extracts showed a minimum inhibitory concentration (MIC) ranging from 78 to 5000\u2009\u03bcg\/mL for antibacterial activity against at least 2 species of bacteria, although none was active against\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    . Antifungal activity was found only for\n                    <jats:italic toggle=\"yes\">L. pseudo-thea<\/jats:italic>\n                    (MIC, 625\u2009\u03bcg\/mL for\n                    <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                    ) and\n                    <jats:italic toggle=\"yes\">L. sidoides<\/jats:italic>\n                    (MIC, 625\u2009\u03bcg\/mL for both\n                    <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">C. neoformans<\/jats:italic>\n                    )\n                    <jats:italic toggle=\"yes\">.<\/jats:italic>\n                    The bioautography showed that flavonoids and coumarins are responsible for the antioxidant activity of the extracts and that the antimicrobial properties are due to flavonoids and terpenoids. The cytotoxic activity was stronger for\n                    <jats:italic toggle=\"yes\">L rubella<\/jats:italic>\n                    extract. To our knowledge, this is the first report of the biological and chemical constituents of\n                    <jats:italic toggle=\"yes\">L. pseudo-thea, L. hermannioides, and L. rubella<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1089\/jmf.2010.0141","type":"journal-article","created":{"date-parts":[[2011,7,15]],"date-time":"2011-07-15T10:31:52Z","timestamp":1310725912000},"page":"840-846","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Identification of Antioxidant and Antimicrobial Compounds of\n                    <i>Lippia<\/i>\n                    Species by Bioautography"],"prefix":"10.1177","volume":"14","author":[{"given":"Rodrigo Luiz","family":"Fabri","sequence":"first","affiliation":[{"name":"Campus Universit\u00e1rio","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro Silva","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Campus Universit\u00e1rio","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussara dos Reis","family":"Moreira","sequence":"additional","affiliation":[{"name":"Campus Universit\u00e1rio","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L\u00facia Morcef","family":"Bouzada","sequence":"additional","affiliation":[{"name":"Campus Universit\u00e1rio","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elita","family":"Scio","sequence":"additional","affiliation":[{"name":"Campus Universit\u00e1rio","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,7,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.1996.9700673"},{"key":"e_1_3_3_3_2","first-page":"1","article-title":"Composi\u00e7\u00e3o qu\u00edmica e atividade biol\u00f3gica de \u00f3leos essenciais de plantas do Nordeste-g\u00eanero Lippia","volume":"33","author":"Bezerra P","year":"1981","unstructured":"Bezerra P, , Fernandes AG, , Craveiro AA et al. 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