{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T20:27:53Z","timestamp":1782851273248,"version":"3.54.5"},"reference-count":24,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p>\n                    In European folk medicine,\n                    <jats:italic toggle=\"yes\">Salvia<\/jats:italic>\n                    species have traditionally been used to enhance memory. In our previous study of 55\n                    <jats:italic toggle=\"yes\">Salvia<\/jats:italic>\n                    taxa, we explored significant anticholinesterase activity of cultivated\n                    <jats:italic toggle=\"yes\">S. fruticosa<\/jats:italic>\n                    . In this study, we compared the inhibitory activity of dichloromethane, ethyl acetate, and ethanol extracts of 3 wild-grown samples and 1 cultivated sample of\n                    <jats:italic toggle=\"yes\">S. fruticosa<\/jats:italic>\n                    against acetylcholinesterase and butyrylcholinesterase enzymes (which are associated with pathogenesis of Alzheimer's disease) by using the spectrophotometric Ellman method. Antioxidant activities were assessed by determining 2,2-diphenyl-1-picrylhydrazyl radical\u2013scavenging activity, iron-chelating capacity, and ferric-reducing antioxidant power. The dichloromethane extract of the cultivated sample was then subjected to fractionation by using open column chromatography and medium-pressure liquid chromatography to obtain the most active fraction by activity-guided fractionation. All fractions and subfractions were tested in the same manner, and inactive subfractions were discarded. The essential oil of the cultivated sample was analyzed by gas chromatography\u2013mass spectrometry.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2010.0158","type":"journal-article","created":{"date-parts":[[2011,6,11]],"date-time":"2011-06-11T15:02:08Z","timestamp":1307804528000},"page":"1476-1483","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Evaluation of Cholinesterase Inhibitory and Antioxidant Activities of Wild and Cultivated Samples of Sage (\n                    <i>Salvia fruticosa<\/i>\n                    ) by Activity-Guided Fractionation"],"prefix":"10.1177","volume":"14","author":[{"given":"Fatma Sezer","family":"\u015eenol","sequence":"first","affiliation":[{"name":"Gazi University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilkay Erdogan","family":"Orhan","sequence":"additional","affiliation":[{"name":"Gazi University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinem Aslan","family":"Erdem","sequence":"additional","affiliation":[{"name":"Ankara University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Kartal","sequence":"additional","affiliation":[{"name":"Ankara University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge","family":"\u015eener","sequence":"additional","affiliation":[{"name":"Gazi University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y\u00fcksel","family":"Kan","sequence":"additional","affiliation":[{"name":"Sel\u00e7uk University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferhat","family":"Celep","sequence":"additional","affiliation":[{"name":"Middle East Technical University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Middle East Technical University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musa","family":"Dogan","sequence":"additional","affiliation":[{"name":"Middle East Technical University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,11,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(03)00502-7"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjopharm.2005.03.005"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0011-393X(03)00059-6"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199612)11:12<1063::AID-GPS532>3.0.CO;2-1"},{"key":"e_1_3_3_6_2","first-page":"57","article-title":"A new record for the Flora of Turkey: Salvia viscosa Jacq","volume":"33","author":"Celep F","year":"2009","unstructured":"Celep F, , Dogan M, , Duran A. A new record for the Flora of Turkey: Salvia viscosa Jacq. (Labiatae). Turk J Bot, 2009; 33:57\u201360.","journal-title":"(Labiatae). Turk J Bot"},{"key":"e_1_3_3_7_2","volume-title":"Istanbul University Publications No 3255","author":"Baytop T","year":"1999","unstructured":"Baytop T. Therapy with Medicinal Plants in Turkey (Past, Present) Istanbul University Publications No 3255. 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Comparison of antioxidant capacities of the leaves and flowers of Salvia fruticosa grown in Turkey. 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