{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:18:47Z","timestamp":1780964327179,"version":"3.54.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>\n                    This study evaluated,\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    , the antimicrobial activity of the hexane extract (JCHE), methanol extract (JCME), and chloroform fraction (JCCF) of bark from\n                    <jats:italic toggle=\"yes\">Jacaranda cuspidifolia<\/jats:italic>\n                    Mart. (Family Bignoniaceae), a Brazilian medicinal plant, traditionally used as anti-syphilis and anti-gonorrhea treatment. The antimicrobial activity was evaluated using the disc diffusion method followed by the determination of minimum inhibitory concentration (MIC) values. JCHE was not active against the bacteria evaluated. JCME presented antibacterial activity against\n                    <jats:italic toggle=\"yes\">Streptococcus pyogenes<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Neisseria gonorrhoeae<\/jats:italic>\n                    with MIC values of 16.3\u2009mg\/mL, 9.1\u2009mg\/mL, and 25.2\u2009mg\/mL, respectively. JCCF was active against\n                    <jats:italic toggle=\"yes\">Staphylococcus epidermidis<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">S. aureus<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Proteus mirabilis<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Serratia marcescens<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">S. pyogenes<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Enterobacter aerogenes<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">N. gonorrhoeae<\/jats:italic>\n                    with MIC values of 18.3\u2009mg\/mL, 9.3\u2009mg\/mL, 6.3\u2009mg\/mL, 6.1\u2009mg\/mL, 9.2\u2009mg\/mL, 6.2\u2009mg\/mL, and 25.2\u2009mg\/mL, respectively. Phytochemical analysis of JCME and JCCF gave positive results for saponins, coumarins, flavonoids, tannins, quinones, alkaloids, triterpenes, and steroids. Verbascoside was isolated and identified as a major peak in JCME and JCCF high-performance liquid chromatography fingerprints and might contribute to the observed antimicrobial activity.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2010.0251","type":"journal-article","created":{"date-parts":[[2011,6,11]],"date-time":"2011-06-11T15:12:06Z","timestamp":1307805126000},"page":"1604-1608","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["<i>Jacaranda cuspidifolia<\/i>\n                    Mart. (Bignoniaceae) as an Antibacterial Agent"],"prefix":"10.1177","volume":"14","author":[{"given":"Ana L\u00facia A.","family":"Arruda","sequence":"first","affiliation":[{"name":"Dom Bosco Catholic University","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla J.B.","family":"Vieira","sequence":"additional","affiliation":[{"name":"Dom Bosco Catholic University","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniella G.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Dom Bosco Catholic University","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regilene F.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Dom Bosco Catholic University","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel O.","family":"Castilho","sequence":"additional","affiliation":[{"name":"Federal University of Minas Gerais","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,12,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2007.11.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3923\/ijp.2008.230.232"},{"key":"e_1_3_3_4_2","volume-title":"Module 1\u2014Introduction to STI Prevention and Control","year":"2007","unstructured":"Module 1\u2014Introduction to STI Prevention and Control. 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