{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:20:32Z","timestamp":1783041632826,"version":"3.54.6"},"reference-count":47,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>\n                    Recent studies indicate that an oil extract from\n                    <jats:italic toggle=\"yes\">Salvia sclarea<\/jats:italic>\n                    may provide clinical benefits in various pathological conditions. In comparison to extracts from other\n                    <jats:italic toggle=\"yes\">Salvia<\/jats:italic>\n                    species,\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil contains twice as much omega-3 fatty acids, which are involved in eicosanoid synthesis pathways, and has been found to contain significant levels of the psychoactive monoterpane linalool. In the present study, we examined the mood stabilizing and anxiolytic-like effects of chronic food administration of\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil extract on behavioral and physiological parameters of mice with prominent dominant and submissive features in behavioral assays used to test mood stabilizing and antidepressant drugs. Experimental animals received oil supplemented food from the age of 4 weeks or from conception via their pregnant dams. Each age group received either\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil\u2013 or sunflower oil\u2013enriched feed. Dominant animals, whose pregnant mothers received\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil\u2013enriched feed from the date of conception, showed a significant reduction of dominant and anxiety-like behavior, in comparison to their sunflower oil\u2013treated counterparts.\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil\u2013treated submissive animals exhibited a similar tendency, and showed a significant reduction in blood corticosterone levels. These findings enforce the hypothesis that\n                    <jats:italic toggle=\"yes\">S. sclarea<\/jats:italic>\n                    oil possesses anxiolytic properties.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2012.0137","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:52:36Z","timestamp":1361976756000},"page":"216-222","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Chronic Food Administration of\n                    <i>Salvia sclarea<\/i>\n                    Oil Reduces Animals' Anxious and Dominant Behavior"],"prefix":"10.1177","volume":"16","author":[{"given":"Moshe","family":"Gross","sequence":"first","affiliation":[{"name":"Ariel University","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elimelech","family":"Nesher","sequence":"additional","affiliation":[{"name":"Ariel University","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Tikhonov","sequence":"additional","affiliation":[{"name":"Ariel University","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Raz","sequence":"additional","affiliation":[{"name":"Ariel University","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Pinhasov","sequence":"additional","affiliation":[{"name":"Ariel University","place":["Israel"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.1202"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10600-010-9688-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/B:CONC.0000039127.56323.3e"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bse.2005.09.002"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/70.3.560s"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2008.12.022"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2009.01.004"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0753-3322(02)00253-6"},{"issue":"1","key":"e_1_3_3_10_2","first-page":"7","article-title":"Dietary requirements for omega-6 and omega-3 PUFAs: is the balance relevant?","volume":"55","author":"Howe P","year":"2009","unstructured":"Howe P, , Buckley J. Dietary requirements for omega-6 and omega-3 PUFAs: is the balance relevant? Ann Nutr Metab, 2009; 55,Suppl 1:7.","journal-title":"Ann Nutr Metab"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5215.2009.00413.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.188.1.46"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v68n0712"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.10.913"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/00048670701827275"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(03)00032-4"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.C500003-JLR200"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2009.02.005"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2006.09.015"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.03.018"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1159\/000056145"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008877-200512000-00009"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-011-9544-0"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2005.03.014"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(03)01272-X"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0270(85)90031-7"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31819773cf"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2754-5"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2647"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1683"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2008.01707.x"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269881112458729"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2007.05.004"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2672"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2010.06.020"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2010.08.026"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2010.09.012"},{"key":"e_1_3_3_38_2","article-title":"Beyond the serotonin hypothesis: mitochondria, inflammation, neurodegeneration in major depression, affective spectrum disorders","author":"Gardner A","year":"2010","unstructured":"Gardner A, , Boles RG. Beyond the serotonin hypothesis: mitochondria, inflammation, neurodegeneration in major depression, affective spectrum disorders. Prog Neuropsychopharmacol Biol Psychiatry, 2010.","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2010.01.005"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2010.04.035"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf900420g"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf101200p"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.031809.130727"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-010-2035-0"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7610.2011.02371.x"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2012.02.010"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2012.02.040"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/annotation\/8f24480c-d341-48e3-8bb2-5e0275941f87"}],"container-title":["Journal of Medicinal Food"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jmf.2012.0137","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jmf.2012.0137","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jmf.2012.0137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:19:57Z","timestamp":1777645197000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jmf.2012.0137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1089\/jmf.2012.0137"],"URL":"https:\/\/doi.org\/10.1089\/jmf.2012.0137","relation":{},"ISSN":["1096-620X","1557-7600"],"issn-type":[{"value":"1096-620X","type":"print"},{"value":"1557-7600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}