{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T01:06:21Z","timestamp":1787965581136,"version":"build-2784847793"},"reference-count":7,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>\n                    The present randomized, double-blind, placebo-controlled study evaluated the efficacy and safety of\n                    <jats:italic toggle=\"yes\">Salacia reticulata<\/jats:italic>\n                    leaves and root bark extracts in 29 patients with prediabetes and mild to moderate hyperlipidemia. Patients received either\n                    <jats:italic toggle=\"yes\">Salacia<\/jats:italic>\n                    extracts (500\u2009mg\/day) or placebo along with therapeutic lifestyle changes for a period of 6 weeks. Efficacy was evaluated in terms of change in lipid profile and glycemic levels. The safety and tolerability was evaluated by a physical examination and clinical laboratory evaluations. Improvements in lipid profiles and glycemic levels were observed in\n                    <jats:italic toggle=\"yes\">Salacia<\/jats:italic>\n                    extract-treated groups when compared to placebo at week 6. A statistical significant reduction was observed in low-density lipoprotein cholesterol and fasting blood sugar (FBS) levels at week 3 and 6 when treated with root bark extract. The leaves extract-treated group showed statistically significant reduction in FBS levels at week 6 only. No adverse events occurred and all safety parameters were within normal ranges during the study. This study revealed that treatment with\n                    <jats:italic toggle=\"yes\">S. reticulata<\/jats:italic>\n                    was safe and well-tolerated and may be beneficial in the management of prediabetes and mild to moderate hyperlipidemia.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2013.2751","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T12:57:27Z","timestamp":1371214647000},"page":"564-568","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":26,"title":["<i>Salacia reticulata<\/i>\n                    Improves Serum Lipid Profiles and Glycemic Control in Patients with Prediabetes and Mild to Moderate Hyperlipidemia: A Double-Blind, Placebo-Controlled, Randomized Trial"],"prefix":"10.1177","volume":"16","author":[{"given":"H.N.","family":"Shivaprasad","sequence":"first","affiliation":[{"name":"Olive Lifesciences Pvt. Ltd.","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bhanumathy","sequence":"additional","affiliation":[{"name":"Olive Lifesciences Pvt. Ltd.","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Sushma","sequence":"additional","affiliation":[{"name":"Olive Lifesciences Pvt. Ltd.","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Midhun","sequence":"additional","affiliation":[{"name":"Olive Lifesciences Pvt. Ltd.","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.R.","family":"Raveendra","sequence":"additional","affiliation":[{"name":"Srinivasa Clinic and Diabetic Care Centre","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.R.","family":"Sushma","sequence":"additional","affiliation":[{"name":"Srinivasa Clinic and Diabetic Care Centre","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Venkateshwarlu","sequence":"additional","affiliation":[{"name":"Srinivasa Clinic and Diabetic Care Centre","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,6,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1091"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2007.tb00998.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.4038\/tare.v13i2.3137"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/86.1.124"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2004.10.026"},{"key":"e_1_3_2_7_2","first-page":"832","article-title":"Salacia oblonga extract reduces postprandial glycemia following a solid, high-starch meal","volume":"21","author":"Hertzler S","year":"2007","unstructured":"Hertzler S, , Washam M, , Williams J. Salacia oblonga extract reduces postprandial glycemia following a solid, high-starch meal. FASEB J, 2007; 21:832\u2013839.","journal-title":"FASEB J"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/diaspect.22.4.206"}],"container-title":["Journal of Medicinal Food"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jmf.2013.2751","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jmf.2013.2751","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jmf.2013.2751","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:21:34Z","timestamp":1777645294000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jmf.2013.2751"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":7,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1089\/jmf.2013.2751"],"URL":"https:\/\/doi.org\/10.1089\/jmf.2013.2751","relation":{},"ISSN":["1096-620X","1557-7600"],"issn-type":[{"value":"1096-620X","type":"print"},{"value":"1557-7600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}