{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T03:39:47Z","timestamp":1785728387110,"version":"3.56.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -Oryzanol, a prevalent compound in pigmented rice varieties, has been reported to ameliorate obesity-associated metabolic disorders. Antiadipogenic activities of\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -oryzanol were determined in human adipose-derived mesenchymal stem cells and mouse-derived 3T3-L1 cells.\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -Oryzanol significantly decreased lipid accumulation and reduced glycerol-3-phosphate dehydrogenase activities in both adipocytes. In addition,\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -oryzanol in four pigmented rice varieties (black with giant embryo, brown, sugary brown, and red) was stable when stored at 4\u00b0C and also at room temperature for 22 weeks, whereas other bioactives such as lutein and\n                    <jats:italic toggle=\"yes\">\u03b2<\/jats:italic>\n                    -carotene were stable only at \u221280\u00b0C. Furthermore, the yield of\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -oryzanol from these rice varieties was significantly increased through steaming and roasting processes. Therefore,\n                    <jats:italic toggle=\"yes\">\u03b3<\/jats:italic>\n                    -oryzanol exerts antiadipogenic activity by suppressing adipocyte differentiations and is stable in pigmented rice for an extended period of time during storage and after cooking. Thus, the intake of pigmented rice may be a useful strategy for preventing obesity.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2015.3647","type":"journal-article","created":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T15:57:11Z","timestamp":1466092631000},"page":"710-715","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Antiadipogenic Activity of\n                    <i>\u03b3<\/i>\n                    -Oryzanol and Its Stability in Pigmented Rice"],"prefix":"10.1177","volume":"19","author":[{"given":"Igor Otavio","family":"Minatel","sequence":"first","affiliation":[{"name":"Tufts University"},{"name":"Botucatu Medical School","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon-Mi","family":"Lee","sequence":"additional","affiliation":[{"name":"Konkuk University"},{"name":"Konkuk University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haelim","family":"Yoon","sequence":"additional","affiliation":[{"name":"Konkuk University"},{"name":"Konkuk University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young","family":"Yoon","sequence":"additional","affiliation":[{"name":"Konkuk University"},{"name":"Konkuk University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Ik","family":"Han","sequence":"additional","affiliation":[{"name":"National Institute of Crop Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Renata","family":"Correa","sequence":"additional","affiliation":[{"name":"Botucatu Medical School","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Fecchio","sequence":"additional","affiliation":[{"name":"Botucatu Medical School","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Jin","family":"Yeum","sequence":"additional","affiliation":[{"name":"Konkuk University"},{"name":"Konkuk University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2004.08.039"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7666"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1079\/PNS2002222"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/76.2.390"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2003592"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.109"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11746-002-0628-x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1024\/0300-9831.78.6.293"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2006.03.006"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200700011"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2011.11.028"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/10715760290025960"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2006.08.003"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1089\/10966200152744481"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.3.744"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2014.3146"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.2337\/db11-1767"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5198(19)43378-7"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1094\/CC-82-0004"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02537832"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.36.4-SupplementI_S1"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2007.04.005"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(76)90527-3"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.10.5138"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-10-47"},{"key":"e_1_3_3_27_2","article-title":"Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1\/AMPK pathway","volume":"7","author":"He Y","year":"2013","unstructured":"He Y, , Li Y, , Zhao T, , Wang Y, , Sun C: Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1\/AMPK pathway. 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