{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:05:55Z","timestamp":1784041555333,"version":"3.55.0"},"reference-count":48,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medicinal Food"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:p>\n                    \u201cQuelites\u201d are edible plants that are part of the traditional agro-ecosystems in Mexico. These plants, despite their already known nutritional properties, are now considered neglected and underutilized species. With the objective of promoting their reinsertion in the markets and mainly, in daily diets, efforts have been made to study them from multidisciplinary approaches to demonstrate their beneficial properties. To generate evidence of an added health-promoting value that would encourage quelites consumption, in the present work, the anti-\n                    <jats:italic toggle=\"yes\">Helicobacter pylori<\/jats:italic>\n                    activity of three representative quelite species,\n                    <jats:italic toggle=\"yes\">Anoda cristata<\/jats:italic>\n                    (Alache),\n                    <jats:italic toggle=\"yes\">Cnidoscolus aconitifolius<\/jats:italic>\n                    (Chaya), and\n                    <jats:italic toggle=\"yes\">Crotalaria pumila<\/jats:italic>\n                    (Chepil), was tested.\n                    <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                    is considered the etiological agent of gastritis, ulcer, and gastric cancer, and represents a public health problem in Mexico and worldwide. Aqueous (AQ) and dichloromethane\u2013methanol (DM) extracts were obtained from the three species of quelites to investigate their effect on\n                    <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                    growth and on two of its colonization factors (adherence and urease activity). DM extracts from Chaya, Chepil, and Alache exert the best inhibitory effect on bacterial growth, with minimum inhibitory concentrations of 62.5, 125, and 250\u2009\n                    <jats:italic toggle=\"yes\">\u03bc<\/jats:italic>\n                    g\/mL, respectively. AQ and DM extracts inhibit bacterial adhesion by 30% to 50%. None of them has an effect on urease activity. The two flavonoids present in\n                    <jats:italic toggle=\"yes\">A. cristata<\/jats:italic>\n                    , acacetin and diosmetin, inhibit\n                    <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                    growth by \u223c90% with 3.9\u2009\n                    <jats:italic toggle=\"yes\">\u03bc<\/jats:italic>\n                    g\/mL. These results provide new information about the anti-\n                    <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                    potential of three edible quelites, and give an added value, since their routine consumption may impact on the prevention and\/or control of\n                    <jats:italic toggle=\"yes\">H. pylori-<\/jats:italic>\n                    associated diseases.\n                  <\/jats:p>","DOI":"10.1089\/jmf.2017.0137","type":"journal-article","created":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T14:25:30Z","timestamp":1532355930000},"page":"1150-1157","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Anti-\n                    <i>Helicobacter pylori<\/i>\n                    Potential of Three Edible Plants Known as Quelites in Mexico"],"prefix":"10.1177","volume":"21","author":[{"given":"Erika","family":"Gomez-Chang","sequence":"first","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guadalupe Vanessa","family":"Uribe-Estanislao","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maricruz","family":"Martinez-Martinez","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"G\u00e1lvez-Mariscal","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma","family":"Romero","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,15]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"109","article-title":"Quelites-Ethnoecology of edible greens past, present, and future","volume":"1","author":"Bye RA","year":"1981","unstructured":"Bye RA: Quelites-Ethnoecology of edible greens past, present, and future. J Ethnobiol, 1981; 1:109\u2013123.","journal-title":"J Ethnobiol"},{"key":"e_1_3_3_3_2","unstructured":"Padulosi S Thompson J Rudebjer P: What are NUS? Why are they important? In: Fighting poverty hunger and malnutrition with neglected and underutilized species (NUS): Needs challenges and the way forward Bioversity International Rome 2013 pp. 9\u201319. www.bioversityinternational.org\/fileadmin\/_migrated\/uploads\/tx_news\/Fighting_poverty__hunger_and_malnutrition_with_neglected_and_underutilized_species__NUS__1671.pdf (accessed October2017)."},{"key":"e_1_3_3_4_2","unstructured":"Linares Mazari E Bye Boettler R: The underutilized species of the milpa [In Spanish]. University Digital Magazine (Online) published May 1 2015; ISSN 1607\u20136079. www.revista.unam.mx\/vol.16\/num5\/art35\/art35.pdf (accessed July13 2018)."},{"key":"e_1_3_3_5_2","first-page":"11","article-title":"Quelites, edible plants of Mexico: a reflection on cultural exchange [In Spanish]","volume":"31","author":"Bye R","year":"2000","unstructured":"Bye R, , Linares E: Quelites, edible plants of Mexico: a reflection on cultural exchange [In Spanish]. Biodiversitas, 2000; 31:11\u201314.","journal-title":"Biodiversitas"},{"key":"e_1_3_3_6_2","unstructured":"Argueta V Cano J Rodarte M: Atlas of the traditional Mexican medicine plants [In Spanish]. National Institute of Indigenous Affairs Mexico 1994."},{"key":"e_1_3_3_7_2","unstructured":"The National Service for Seed Inspection and Certification Genetic Resources for Food and Agriculture. 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