{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T13:15:37Z","timestamp":1775135737055,"version":"3.50.1"},"reference-count":0,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1997,6,1]],"date-time":"1997-06-01T00:00:00Z","timestamp":865123200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ocular Pharmacology and Therapeutics"],"published-print":{"date-parts":[[1997,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In this study, the effect of subconjunctival retention of perfluoropropane (C\n                    <jats:sub>3<\/jats:sub>\n                    F\n                    <jats:sub>8<\/jats:sub>\n                    ) gas on trabeculectomy was evaluated to determine if this maneuver would increase the success rate of the surgery. Thirty-two patients (under 35 years old) with a diagnosis of primary open-angle glaucoma or steroid-induced glaucoma were randomized into two groups to receive trabeculectomy: Group A (trabeculectomy alone, 16 eyes) and Group B (trabeculectomy with subconjunctival retention of 0.5 mL pure C\n                    <jats:sub>3<\/jats:sub>\n                    F\n                    <jats:sub>8<\/jats:sub>\n                    gas, 16 eyes). The results showed that the typical appearance of a subconjunctivally retained C\n                    <jats:sub>3<\/jats:sub>\n                    F\n                    <jats:sub>8<\/jats:sub>\n                    filtering bleb is highly distended in the first two weeks after surgery, followed by flattening and diffusing gradually. The average retention time of C\n                    <jats:sub>3<\/jats:sub>\n                    F\n                    <jats:sub>8<\/jats:sub>\n                    gas within the subconjunctival space is 28 \u00b1 6 days. A higher success rate was noted in Group B than in Group A (94% versus 50%, p = 0.016) at a mean follow-up time of 12 months. However, there were no differences in complication rates and results of final visual acuity between the two groups (both groups had two patients lose more than two lines of vision, p=1.0). Our study suggests that subconjunctival retention of C\n                    <jats:sub>3<\/jats:sub>\n                    F\n                    <jats:sub>8<\/jats:sub>\n                    gas increases the success rate of trabeculectomy in young people in the intermediate-term (12 months) follow-up period.\n                  <\/jats:p>","DOI":"10.1089\/jop.1997.13.235","type":"journal-article","created":{"date-parts":[[2009,1,30]],"date-time":"2009-01-30T06:38:47Z","timestamp":1233297527000},"page":"235-242","source":"Crossref","is-referenced-by-count":3,"title":["Subconjunctival Retention of C\n                    <sub>3<\/sub>\n                    F\n                    <sub>8<\/sub>\n                    Gas Increased the Success Rates of Trabeculectomy in Young People"],"prefix":"10.1177","volume":"13","author":[{"given":"DA-WEN","family":"LU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MING-CHEN","family":"TAI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CHIAO-HSI","family":"CHIANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,1,30]]},"container-title":["Journal of Ocular Pharmacology and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jop.1997.13.235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jop.1997.13.235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T12:21:45Z","timestamp":1775132505000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jop.1997.13.235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,6]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,6]]}},"alternative-id":["10.1089\/jop.1997.13.235"],"URL":"https:\/\/doi.org\/10.1089\/jop.1997.13.235","relation":{},"ISSN":["1080-7683","1557-7732"],"issn-type":[{"value":"1080-7683","type":"print"},{"value":"1557-7732","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,6]]}}}