{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:47:04Z","timestamp":1777909624101,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ocular Pharmacology and Therapeutics"],"published-print":{"date-parts":[[2010,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>\n                      To report the treatment of therapy-resistant\n                      <jats:italic toggle=\"yes\">Pseudomonas aeruginosa<\/jats:italic>\n                      keratitis with topical piperacillin\/tazobactam.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective report of 3 cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Three patients with\n                      <jats:italic toggle=\"yes\">P. aeruginosa<\/jats:italic>\n                      keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin\/tazobactam.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Therapy-resistant\n                      <jats:italic toggle=\"yes\">P. aeruginosa<\/jats:italic>\n                      keratitis acquired from the community is becoming an increasing problem. Topical piperacillin\/tazobactam is an option for the treatment of therapy-resistant\n                      <jats:italic toggle=\"yes\">P. aeruginosa<\/jats:italic>\n                      keratitis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jop.2009.0077","type":"journal-article","created":{"date-parts":[[2010,4,25]],"date-time":"2010-04-25T15:17:03Z","timestamp":1272208623000},"page":"219-222","source":"Crossref","is-referenced-by-count":16,"title":["Topical Piperacillin\/Tazobactam for Recalcitrant\n                    <i>Pseudomonas Aeruginosa<\/i>\n                    Keratitis"],"prefix":"10.1177","volume":"26","author":[{"given":"Fiona LM","family":"Chew","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TK","family":"Soong","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoy Choong","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Samsudin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subrayan","family":"Visvaraja","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, University of Malaya, Kuala Lumpur, Malaysia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,4,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000027291"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg270"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/338782"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(98)00045-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2009.02.003"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00179-2"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.40360"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.45637-0"},{"issue":"41","key":"e_1_3_3_10_2","first-page":"22","article-title":"Mechanisms of antibiotic resistance in Pseudomonas aeruginosa","volume":"95","author":"Lambert P.A.","year":"2002","unstructured":"Lambert P.A. Mechanisms of antibiotic resistance in Pseudomonas aeruginosa. J. R. Soc. Med. 95(Suppl 41 ): 22\u201326, 2002.","journal-title":"J. R. Soc. 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