{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:14:25Z","timestamp":1787775265918,"version":"build-2784847793"},"reference-count":60,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ocular Pharmacology and Therapeutics"],"published-print":{"date-parts":[[2019,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To report tolerability, safety, and efficacy of a topical triamcinolone acetonide-loaded liposomes formulation (TA-LF) in targeting the macular area in patients with refractory pseudophakic cystoid macular edema (PCME).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>For tolerability, safety and efficacy evaluation, 12 eyes of 12 patients with refractory PCME were exposed to one drop of TA-LF (TA at 0.2%) every 2\u2009h for 90 days or until best-corrected visual acuity (BCVA) was achieved. Intraocular pressure (IOP), slit lamp examination, and central foveal thickness (CFT) were analyzed at every visit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Patients with refractory PCME under TA-LF therapy showed a significant improvement in BVCA and CFT without significant IOP modification (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u20090.94). On average CFT decreased to 206.75\u2009\u00b1\u2009135.72\u2009\u03bcm and BCVA improved to 20.08\u2009\u00b1\u200910.35 letters (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.0005). BCVA was achieved at 10.58\u2009\u00b1\u20096.70 weeks (range 2\u201318). TA-LF was well tolerated in all cases. Neither ocular surface abnormalities nor adverse events were recorded.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>TA-LF was well tolerated and improved BCVA and CFT on patients with refractory PCME.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jop.2018.0101","type":"journal-article","created":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T14:35:54Z","timestamp":1546871754000},"page":"106-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Novel Triamcinolone Acetonide-Loaded Liposomes Topical Formulation for the Treatment of Cystoid Macular Edema After Cataract Surgery: A Pilot Study"],"prefix":"10.1177","volume":"35","author":[{"given":"Alejandro","family":"Gonzalez-De la Rosa","sequence":"first","affiliation":[{"name":"Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Zapopan, M\u00e9xico."},{"name":"Centro de Retina Medica y Quir\u00fargica, S.C., Centro Medico Puerta de Hierro. Zapopan, Jalisco, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Navarro-Partida","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Zapopan, M\u00e9xico."},{"name":"Centro de Retina Medica y Quir\u00fargica, S.C., Centro Medico Puerta de Hierro. Zapopan, Jalisco, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Altamirano-Vallejo","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Zapopan, M\u00e9xico."},{"name":"Centro de Retina Medica y Quir\u00fargica, S.C., Centro Medico Puerta de Hierro. Zapopan, Jalisco, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada Gabriela","family":"Hernandez-Gamez","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Aut\u00f3noma de San Luis Potos\u00ed, San Luis Potos\u00ed, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus Javier","family":"Garcia-Ba\u00f1uelos","sequence":"additional","affiliation":[{"name":"Instituto de Biolog\u00eda Molecular y Terapia G\u00e9nica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Armendariz-Borunda","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Zapopan, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arturo","family":"Santos","sequence":"additional","affiliation":[{"name":"Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Zapopan, M\u00e9xico."},{"name":"Centro de Retina Medica y Quir\u00fargica, S.C., Centro Medico Puerta de Hierro. 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