{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:52:15Z","timestamp":1777909935962,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Ocular Pharmacology and Therapeutics"],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To evaluate the effect of Mydrane (contains tropicamide, phenylephrine hydrochloride, and lidocaine hydrochloride) on time needed to induce mydriasis and mydriasis stability during cataract surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was an observational, non-interventional, multicenter study of patients undergoing cataract surgery who received Mydrane for mydriasis and intraocular anesthesia. The study was conducted at seven ophthalmology departments at university hospitals in Poland. Patients admitted for cataract surgery within a 2-week period were asked to participate in the study. Patients whose pupils dilated to a diameter \u22656\u2009mm after topical mydriatic administration during preoperative examinations were scheduled to receive Mydrane and included in the registry. No additional inclusion criteria were used. Patients' medical histories, examination results, and operative details were recorded. Pupil diameter was measured during surgery. Surgeons were asked to complete a Likert-based survey in parallel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 307 patients were enrolled. The mean pupil diameter was 7.0\u2009\u00b1\u20091.0\u2009mm before capsulorhexis and 6.9\u2009\u00b1\u20091.2\u2009mm before lens implementation. A pupil diameter \u22656\u2009mm was achieved in 91.9% and 87.6% of patients before capsulorhexis and lens implantation, respectively. We asked 58 surgeons whether they agreed with the statement \u201cMydriasis was obtained in a short time after the administration of Mydrane\u201d; the surgeons agreed with this statement after 92.2% (283\/307) of surgeries. In addition, after 88.2% of surgeries, the surgeons agreed with the statement \u201cMydriasis was stable after the administration of Mydrane.\u201d<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Mydriasis was rapidly and stably obtained after Mydrane injection, as demonstrated by pupil diameter measurements during surgery and surgeons' feedback.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jop.2020.0001","type":"journal-article","created":{"date-parts":[[2020,11,12]],"date-time":"2020-11-12T12:31:44Z","timestamp":1605184304000},"page":"740-746","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Stable Mydriasis After Intracameral Injection of a Combination of Mydriatics and Anesthetic During Cataract Surgery: A Real-Life, Multicenter Study"],"prefix":"10.1177","volume":"36","author":[{"given":"Dariusz","family":"K\u0119cik","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iwona","family":"Grabska-Liberek","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical Centre for Postgraduate Education, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Jurowski","sequence":"additional","affiliation":[{"name":"Department of Eye Diseases, Medical University of Lodz, Lodz, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Mrukwa-Kominek","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wojciech","family":"Omulecki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University of Lodz, University Hospital No 1, Lodz, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u017cena","family":"Romanowska-Dixon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Ocular Oncology, Jagiellonian University Medical College, Cracow, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek P.","family":"Szaflik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanda","family":"Romaniuk","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerzy","family":"Szaflik","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota","family":"Kopacz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Mianowska","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,11]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2015.06.031"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.12.050"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12256"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.11.002"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2017.05.031"},{"key":"e_1_3_4_7_2","unstructured":"European Medicines Agency Science Medicines Health. List of nationally authorised medicinal products. Human Medicines Evaluation Division 2017. Available at www.ema.europa.eu\/docs\/en_GB\/document_library\/Periodic_safety_update_single_assessment\/2017\/09\/WC500234426.pdf (last accessed September1 2017)."},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307587"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310510"},{"key":"e_1_3_4_10_2","volume-title":"Registries for Evaluating Patient Outcomes: A User's Guide","author":"Gliklich R.E.","year":"2014","unstructured":"AHRQ methods for effective health care. In: Gliklich R.E., , Dreyer N.A., , Leavy M.B., eds. Registries for Evaluating Patient Outcomes: A User's Guide. Rockville, MD: Agency for Healthcare Research and Quality; 2014."},{"key":"e_1_3_4_11_2","unstructured":"Bertram D. Likert scales. 2016. Available at http:\/\/my.ilstu.edu\/~eostewa\/497\/Likert%20topic-dane-likert.pdf (last accessed July18 2006)."},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_3_4_13_2","unstructured":"Mydrane. Summary of the product characteristics. Available at http:\/\/pub.rejestrymedyczne.csioz.gov.pl\/ProduktSzczegoly.aspx?id=34888 Accessed October28 2020."},{"key":"e_1_3_4_14_2","volume-title":"Version October","author":"Chylack L.T","year":"2010","unstructured":"Chylack L.TJr.. Instructions for applying the Lens Opacities Classification System, version III (LOCS III) in grading human age-related cataracts. Version October, 6, 2010."},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.10.1173"},{"key":"e_1_3_4_16_2","first-page":"29","article-title":"Iris colour classification scales\u2014then and now","volume":"59","author":"Grigore M.","year":"2015","unstructured":"Grigore M., , and Avram A. Iris colour classification scales\u2014then and now. Rom. J. Ophthalmol. 59:29\u201333, 2015.","journal-title":"Rom. J. Ophthalmol"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2017.02.030"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2014.01.005"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.08.039"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000322"}],"container-title":["Journal of Ocular Pharmacology and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jop.2020.0001","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jop.2020.0001","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jop.2020.0001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:43:56Z","timestamp":1777646636000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jop.2020.0001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,1]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,12,1]]}},"alternative-id":["10.1089\/jop.2020.0001"],"URL":"https:\/\/doi.org\/10.1089\/jop.2020.0001","relation":{},"ISSN":["1080-7683","1557-7732"],"issn-type":[{"value":"1080-7683","type":"print"},{"value":"1557-7732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,1]]}}}