{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:19:39Z","timestamp":1777915179508,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:00:00Z","timestamp":1648598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Palliative Medicine"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Palliative care providers are increasingly using lidocaine infusions for refractory cancer pain. Hoigne syndrome (HS) is a rare psychiatric reaction that has been reported after local anesthetic usage, but has not been described in the palliative care setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report:<\/jats:title>\n                    <jats:p>We report a case of a young woman with metastatic Ewing sarcoma who developed HS days after starting a lidocaine infusion. Given the improvement in her pain since initiation of lidocaine, the decision was made to continue the infusion and medically manage her HS. She had improvement with the addition of benzodiazepines and lowering the lidocaine infusion rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Palliative care providers should be aware of HS as a possible side effect of lidocaine infusions and the unique challenges in managing it in patients near the end of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jpm.2021.0265","type":"journal-article","created":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T15:06:15Z","timestamp":1636383975000},"page":"690-692","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hoigne Syndrome Secondary to Intravenous Lidocaine in a Woman with Metastatic Ewing Sarcoma"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4099-6282","authenticated-orcid":false,"given":"Michael","family":"Spiker","sequence":"first","affiliation":[{"name":"Department of Medicine, West Los Angeles VA Medical Center, Los Angeles, California, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1413-482X","authenticated-orcid":false,"given":"Emily","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA Medical Center, Los Angeles, California, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Karlin","sequence":"additional","affiliation":[{"name":"Department of Medicine, UCLA Medical Center, Los Angeles, California, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,30]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2018.0257"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2015.06.058"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6394(1996)4:3<139::AID-DA7>3.0.CO;2-B"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.144.2.159"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.2190\/KNQT-UEU4-GAQ2-57L6"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2017.136"},{"key":"e_1_3_4_8_2","first-page":"1358","article-title":"Case report: Limbic system activation by intravenous lidocaine in a patient with a complex regional pain syndrome and major depression","author":"Leong MS","year":"2000","unstructured":"Leong MS, , Brent Solvason H: Case report: Limbic system activation by intravenous lidocaine in a patient with a complex regional pain syndrome and major depression. Pain Med, 2000; 1358\u2013361.","journal-title":"Pain Med"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(51)91439-0"},{"key":"e_1_3_4_10_2","first-page":"1350","article-title":"Anaphylactic shock and acute nonallergic reactions following procaine-penicillin","volume":"89","author":"Hoigne R","year":"1959","unstructured":"Hoigne R, , Schoch K: Anaphylactic shock and acute nonallergic reactions following procaine-penicillin. Schweiz Med Wochenschsr, 1959; 89:1350\u20131356.","journal-title":"Schweiz Med Wochenschsr"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-9877(94)90128-7"},{"key":"e_1_3_4_12_2","first-page":"35199","article-title":"Hoigne syndrome following an intravenous injection of ceftriaxone: A case report","author":"Landais A","year":"2014","unstructured":"Landais A, , Marty N, , Bessis D, et al.: Hoigne syndrome following an intravenous injection of ceftriaxone: A case report. 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