{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:19:45Z","timestamp":1777915185138,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Palliative Medicine"],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Respiration with mandibular movement (RMM) is one of the important clinical signs of impending death. However, there is very limited data on its natural course.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective and Methods:<\/jats:title>\n                    <jats:p>This study was conducted in 23 inpatient palliative care units in Japan. It aimed to explore the natural course of RMM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among a total of 1526 cancer patients included, 1065 patients (69.8%) had RMM. A total of 14.8% patients experienced respiratory arrest within 30 minutes from RMM onset, 14.3% within 30\u201360 minutes, 34.4% within 1\u20134 hours, 17.5% within 4\u201312 hours, 8.9% within 12\u201324 hours, and 10.4%&gt; 24 hours. Mean oxygen saturation and percentage of patients with SpO\n                      <jats:sub>2<\/jats:sub>\n                      \u226590% at RMM onset were found to be significantly higher in patients with longer durations from RMM onset to death (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>RMM occurred in a majority (80%) of dying patients within 12 hours. A minority of the patients survived &gt;24 hours.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jpm.2021.0328","type":"journal-article","created":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T09:35:24Z","timestamp":1640770524000},"page":"461-464","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Epidemiology of Respiration with Mandibular Movement in Advanced Cancer Patients: A Multicenter Prospective Cohort Study"],"prefix":"10.1177","volume":"25","author":[{"given":"Keisuke","family":"Kaneishi","sequence":"first","affiliation":[{"name":"Department of Palliative Care Unit, JCHO Tokyo Shinjuku Medical Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Morita","sequence":"additional","affiliation":[{"name":"Palliative and Supportive Care Division, Seirei Mikatahara Hospital, Hamamatsu, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kohara","sequence":"additional","affiliation":[{"name":"Department of Palliative Care, Hiroshima Prefectural Hospital, Hiroshima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Palliative Care, Japanese Red Cross Medical Center, Tokyo, Japan."},{"name":"Department of Palliative Medicine and Advanced Clinical Oncology, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Hospice, The Japan Baptist Hospital, Kyoto, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Nishi","sequence":"additional","affiliation":[{"name":"Kawasaki Municipal Ida Hospital, Kawasaki Comprehensive Care Center, Kawasaki, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Tohoku University School of Medicine, Sendai, Miyagi, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Oyamada","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, JORTC Data Center, Tokyo, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Mori","sequence":"additional","affiliation":[{"name":"Palliative and Supportive Care Division, Seirei Mikatahara Hospital, Hamamatsu, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2013-0457"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/104990919801500407"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/1049909117733661"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29602"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2020.07.031"},{"key":"e_1_3_5_7_2","first-page":"4939","article-title":"Incidence and associated factors of sudden unexpected death in advanced cancer patients: A multicenter prospective cohort study","volume":"10","author":"Satoko Ito","unstructured":"Satoko Ito, , Tatsuya Morita, , Yu Uneno, et al.: Incidence and associated factors of sudden unexpected death in advanced cancer patients: A multicenter prospective cohort study. Cancer Med 202;10:4939\u20134947.","journal-title":"Cancer Med"}],"container-title":["Journal of Palliative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jpm.2021.0328","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jpm.2021.0328","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jpm.2021.0328","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:13:04Z","timestamp":1777655584000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jpm.2021.0328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,1]]}},"alternative-id":["10.1089\/jpm.2021.0328"],"URL":"https:\/\/doi.org\/10.1089\/jpm.2021.0328","relation":{},"ISSN":["1096-6218","1557-7740"],"issn-type":[{"value":"1096-6218","type":"print"},{"value":"1557-7740","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,1]]}}}