{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:36:52Z","timestamp":1777916212548,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Little is known about the prevalence and cumulative burden of coexisting health conditions including chronic joint and muscular pain, urinary incontinence (UI), depression, osteoporosis risk, moderate\/severe vasomotor symptoms, and vulvar\/vaginal atrophy (VVA). We surveyed a nationally representative U.S. sample of midlife (age 40\u201364 years) women to ascertain the prevalence, general health-related quality of life (HRQoL), and health-seeking behaviors associated with these six conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This cross-sectional, telephone survey collected data from a sample of English- and Spanish-speaking U.S. women. The survey contained demographic and menopausal status questions, and also five condition-specific symptom\/disease risk-screening instruments. The EuroQol 5 dimensions (EQ-5D) questionnaire was used to measure HRQoL. Health-seeking behavior was measured based on clinician discussion of and recent treatment for each condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Three thousand fifty eight women (mean age 53.4 years) completed the survey. The majority were white (75.6%), married (60.5%), employed full- or part-time (59.0%), and postmenopausal (69.8%; based on self-report). The prevalence [95% confidence interval] of 0, 1, 2, and \u22653 conditions was 35.2% [33.5\u201336.9], 34.2% [32.5\u201335.9], 17.9% [16.6\u201319.3], and 12.7% [11.5\u201313.9], respectively. Osteoporosis risk (30.6%) was most prevalent, followed by VVA (27.8%) and UI (26.6%). UI and VVA coexisted most frequently (11.3%), followed by osteoporosis risk and VVA (9.8%). EQ-5D scores decreased with increasing number of illnesses (0, 1, 2, and \u22653 conditions, means: 0.92, 0.87, 0.77, 0.61, respectively;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.01). Health-seeking behavior varied by condition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Over 25% of women surveyed had multiple coexisting conditions. Lower HRQoL was associated with multiple conditions and with each added condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2014.4907","type":"journal-article","created":{"date-parts":[[2015,5,14]],"date-time":"2015-05-14T14:12:48Z","timestamp":1431612768000},"page":"374-383","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["The Impact of Multimorbidity on Quality of Life Among Midlife Women: Findings from a U.S. Nationally Representative Survey"],"prefix":"10.1177","volume":"24","author":[{"given":"Kathleen","family":"Lang","sequence":"first","affiliation":[{"name":"Boston Health Economics, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivy M.","family":"Alexander","sequence":"additional","affiliation":[{"name":"University of Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Simon","sequence":"additional","affiliation":[{"name":"George Washington University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Sussman","sequence":"additional","affiliation":[{"name":"Boston Health Economics, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Lin","sequence":"additional","affiliation":[{"name":"Boston Health Economics, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Menzin","sequence":"additional","affiliation":[{"name":"Boston Health Economics, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Friedman","sequence":"additional","affiliation":[{"name":"Mount Auburn Professional Services"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Dutwin","sequence":"additional","affiliation":[{"name":"Social Science Research Solutions"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew G.","family":"Bushmakin","sequence":"additional","affiliation":[{"name":"Pfizer Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maia","family":"Thrift-Perry","sequence":"additional","affiliation":[{"name":"Pfizer Inc."},{"name":"Atrium Staffing, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Altomare","sequence":"additional","affiliation":[{"name":"Pfizer Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Ann","family":"Hsu","sequence":"additional","affiliation":[{"name":"Pfizer Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,5,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.11.1311"},{"key":"e_1_3_3_3_2","unstructured":"Kessler RC. 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