{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:25:04Z","timestamp":1788175504359,"version":"build-2803163510"},"reference-count":86,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T00:00:00Z","timestamp":1453075200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>Preeclampsia affects \u223c3%\u20137% of all pregnancies and is the third leading cause of maternal mortality globally. Growing evidence indicates that preeclampsia results from vascular dysfunction, which also increases the risk for future cardiovascular events. Until recently, preeclampsia was considered a disorder limited to pregnancy, which fully resolved with the delivery of the placenta; however, it is now clear that women with a history of preeclampsia have approximately double the risk of future cardiovascular events compared to women with normotensive pregnancies. The aims of this review were to describe the hemodynamic and vascular changes that occur in normal and preeclamptic pregnancies, to review noninvasive methods to test vascular function, and to discuss the associated increased cardiovascular disease risk related to preeclampsia.<\/jats:p>","DOI":"10.1089\/jwh.2015.5414","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T11:36:52Z","timestamp":1453117012000},"page":"284-291","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":69,"title":["Preeclampsia and Vascular Function: A Window to Future Cardiovascular Disease Risk"],"prefix":"10.1177","volume":"25","author":[{"given":"Davaasambuu","family":"Enkhmaa","sequence":"first","affiliation":[{"name":"National Center for Maternal and Child Health","place":["Mongolia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Wall","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puja K.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer J.","family":"Stuart","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital"},{"name":"Harvard T.H. Chan School of Public Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet Wilson","family":"Rich-Edwards","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital"},{"name":"Harvard T.H. Chan School of Public Health"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Noel Bairey","family":"Merz","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrisandra","family":"Shufelt","sequence":"additional","affiliation":[{"name":"Cedars-Sinai Heart Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,1,18]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"1","article-title":"Deaths: Final data for 2009","volume":"60","author":"Kochanek KD","year":"2011","unstructured":"Kochanek KD, , Xu J, , Murphy SL, , Minino AM, , Kung HC. Deaths: Final data for 2009. Natl Vital Stat Rep, 2011; 60:1\u2013116.","journal-title":"Natl Vital Stat Rep"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxt006"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.044784"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-013-9762-6"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407866-6.00003-1"},{"key":"e_1_3_3_7_2","first-page":"1122","article-title":"Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy","volume":"122","author":"American College of Obstetricians and Gynecologists; Task Force on Hypertension in Pregnancy","year":"2013","unstructured":"American College of Obstetricians and Gynecologists; Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy. Obstet Gynecol, 2013; 122:1122\u20131131.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2014.02.001"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00298.2003"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12191"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.943407"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.02.005"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(93)90405-8"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1967.tb03956.x"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90900-9"},{"key":"e_1_3_3_16_2","first-page":"1000","article-title":"Quantitative estimation of human uterine artery blood flow and pelvic blood flow redistribution in pregnancy","volume":"80","author":"Palmer SK","year":"1992","unstructured":"Palmer SK, , Zamudio S, , Coffin C, , Parker S, , Stamm E, , Moore LG. Quantitative estimation of human uterine artery blood flow and pelvic blood flow redistribution in pregnancy. Obstet Gynecol, 1992; 80:1000\u20131006.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.187039"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(01)00236-X"},{"key":"e_1_3_3_19_2","first-page":"383","article-title":"Forearm blood flow in pre-eclampsia","volume":"110","author":"Bowyer L","year":"2003","unstructured":"Bowyer L, , Brown MA, , Jones M. Forearm blood flow in pre-eclampsia. BJOG, 2003; 110:383\u2013391.","journal-title":"BJOG"},{"key":"e_1_3_3_20_2","first-page":"H821","article-title":"Normal pregnancy is associated with enhanced endothelium-dependent flow-mediated vasodilation","volume":"276","author":"Dorup I","year":"1999","unstructured":"Dorup I, , Skajaa K, , Sorensen KE. Normal pregnancy is associated with enhanced endothelium-dependent flow-mediated vasodilation. Am J Physiol, 1999; 276:H821\u2013H825.","journal-title":"Am J Physiol"},{"key":"e_1_3_3_21_2","first-page":"H748","article-title":"Nitric oxide-mediated vasodilation in human pregnancy","volume":"272","author":"Williams DJ","year":"1997","unstructured":"Williams DJ, , Vallance PJ, , Neild GH, , Spencer JA, , Imms FJ. Nitric oxide-mediated vasodilation in human pregnancy. Am J Physiol, 1997; 272:H748\u2013H752.","journal-title":"Am J Physiol"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000217859.27864.19"},{"key":"e_1_3_3_23_2","first-page":"177","article-title":"The role of the spiral arteries in the pathogenesis of preeclampsia","volume":"1","author":"Brosens IA","year":"1972","unstructured":"Brosens IA, , Robertson WB, , Dixon HG. The role of the spiral arteries in the pathogenesis of preeclampsia. Obstet Gynecol Annu, 1972; 1:177\u2013191.","journal-title":"Obstet Gynecol Annu"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2014.71"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08107.x"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08089.x"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI17189"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1429"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C300012200"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.09.016"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.12.052"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12128"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3282f16a9c"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1080\/08037050500238568"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/hy0202.098325"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2007.49"},{"key":"e_1_3_3_37_2","first-page":"831","article-title":"[Radial augmentation index is associated with cardiovascular risk and arterial stiffness]","volume":"50","author":"Xiao WK","year":"2011","unstructured":"Xiao WK, , Ye P, , Luo LM, , Liu DJ, , Wu HM. [Radial augmentation index is associated with cardiovascular risk and arterial stiffness]. Zhonghua Nei Ke Za Zhi, 2011; 50:831\u2013835.","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328336c8e9"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet256"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aet400"},{"key":"e_1_3_3_41_2","unstructured":"Nichols WW O'Rourkey MF. McDonald's blood flow in arteries: Theoretical experimental and clinical principles 5th ed. London: Hodder Arnold 2005."},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2000.t01-1-00263.x"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e32832941ce"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32832e94e7"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.10.061"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000105767.94169.E3"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000090"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006134"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12145"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130898"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3283588189"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2011.06.016"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.106062"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2012.1"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.01.104"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-14-98"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjhyper.2004.05.018"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1081\/PRG-200059871"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32834e4b0f"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641960902890176"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2014.10.145"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2014.913608"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.948455"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2012-0248"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11183"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01906.x"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2014.62"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38380.674340.E0"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39366.416817.BE"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.128751"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.07.024"},{"issue":"58","key":"e_1_3_3_72_2","first-page":"e51","article-title":"A history of preeclampsia identifies women who have underlying cardiovascular risk factors","volume":"200","author":"Smith GN","year":"2009","unstructured":"Smith GN, , Walker MC, , Liu A, et al. A history of preeclampsia identifies women who have underlying cardiovascular risk factors. Am J Obstet Gynecol, 2009; 200:58:e51\u2013e58.","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31828ea3b5"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1097\/JIM.0000000000000189"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2008.03.004"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7394.845"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.385301.BE"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181bb0dfc"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.06.042"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000152912.02042.cd"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.04850"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.112.198366"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13057"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2014.10.012"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2014.10.081"},{"key":"e_1_3_3_86_2","first-page":"267","article-title":"Assessing cardiovascular disease risk among young women with a history of delivering a low-birth-weight infant","volume":"30","author":"Dietz PM","year":"2013","unstructured":"Dietz PM, , Kuklina EV, , Bateman BT, , Callaghan WM. Assessing cardiovascular disease risk among young women with a history of delivering a low-birth-weight infant. Am J Perinatol, 2013; 30:267\u2013273.","journal-title":"Am J Perinatol"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.04.001"}],"container-title":["Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jwh.2015.5414","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2015.5414","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2015.5414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T21:21:23Z","timestamp":1781558483000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jwh.2015.5414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,18]]},"references-count":86,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1089\/jwh.2015.5414"],"URL":"https:\/\/doi.org\/10.1089\/jwh.2015.5414","relation":{},"ISSN":["1540-9996","1931-843X"],"issn-type":[{"value":"1540-9996","type":"print"},{"value":"1931-843X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,18]]}}}