{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:40:33Z","timestamp":1777916433433,"version":"3.51.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>There have been limited data on sex-specific risk factors for coronary artery disease (CAD) in patients with stable chest pain. This study was performed to investigate whether risk factors for CAD differ by sex in stable symptomatic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data were obtained from a nation-wide registry, enrolling 1025 patients (age, 62.0\u2009\u00b1\u200911.0 years, 587 women) with chest pain who underwent elective invasive coronary angiography under the suspicion of CAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 373 patients (36.4%) had obstructive CAD (\u226550% stenosis) (men vs. women: 33.8% vs. 38.3%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.135). In men, univariate analyses showed that age, renal function, total cholesterol, low-density lipoprotein cholesterol, triglyceride, C-reactive protein (CRP), left ventricular (LV) systolic function, and septal annular velocity of LV (e\u2032) were significantly associated with the presence of obstructive CAD. Among these factors, a high CRP level (\u22650.50\u2009mg\/dL) was an independent predictor of CAD in multivariable analysis (odds ratio [OR], 2.93; 95% confidence interval [CI], 1.26\u20136.82;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.012). In women, univariate analyses showed that age, waist circumference, heart rate, hypertension, diabetes mellitus, low high-density lipoprotein cholesterol, LV systolic function, LV mass index, e\u2032 velocity, E\/e\u2032, and left atrial size were significantly associated with the presence of obstructive CAD. Among these factors, lower e\u2032 velocity (&lt;6.35\u2009cm\/s) was an independent predictor of CAD in multivariable analysis (OR, 2.38; 95% CI, 1.21\u20134.70;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.012).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Among patients with stable chest pain, inflammation and LV diastolic dysfunction are independently associated with obstructive CAD in men and women, respectively.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2017.6834","type":"journal-article","created":{"date-parts":[[2018,6,29]],"date-time":"2018-06-29T15:09:37Z","timestamp":1530284977000},"page":"212-219","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Sex Differences in Traditional and Nontraditional Risk Factors for Obstructive Coronary Artery Disease in Stable Symptomatic Patients"],"prefix":"10.1177","volume":"28","author":[{"given":"Hack-Lyoung","family":"Kim","sequence":"first","affiliation":[{"name":"SMG-SNU Boramae Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung-A","family":"Kim","sequence":"additional","affiliation":[{"name":"SMG-SNU Boramae Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohee","family":"Oh","sequence":"additional","affiliation":[{"name":"SMG-SNU Boramae Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Kim","sequence":"additional","affiliation":[{"name":"Korea University Anam Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Ju","family":"Yoon","sequence":"additional","affiliation":[{"name":"Chonnam National University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Mi","family":"Park","sequence":"additional","affiliation":[{"name":"Korea University Anam Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Seung","family":"Shin","sequence":"additional","affiliation":[{"name":"Gachon Medical School Gil Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung-Soon","family":"Hong","sequence":"additional","affiliation":[{"name":"Hallym University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gil Ja","family":"Shin","sequence":"additional","affiliation":[{"name":"Ewha Womans University Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-Joo","family":"Shim","sequence":"additional","affiliation":[{"name":"Korea University Anam Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/1357628031000116808"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31828124ad"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.008720"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn018"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.11.006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.318"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-015-0815-6"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.03.015"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.561647"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2016.02.001"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.5603\/CJ.a2015.0016"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020955"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2015.5381"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2010.25.11.1616"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2014.10.003"},{"key":"e_1_3_2_17_2","unstructured":"Baim DS Grossman W. 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