{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:40:55Z","timestamp":1777916455517,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>A growing number of infertile women undergo assisted reproductive technology (ART). Older maternal age and the presence of comorbidities may affect cardiovascular (CV) women health. Safety aspects are central in risk assessment; we report the experience of internal medicine clinical setting at the ART center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>we investigated 243 infertile women (110 autologous and 133 oocyte donation [OD]); cardiometabolic parameters and CV risk factors were investigated during the clinical evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We observed high prevalence of dyslipidemia (62.9%), smoking habit (27.5%), and body mass index (26.7%). Waist \u226580\u2009cm was present in 65%, and waist to hip ratio (WHR) value &gt;0.80 in 60.5% of women. The prevalence of migraine with aura, hypertension, and diabetes was 5.3%, 4.9%, and 4.5%, respectively. By evaluating variables according to autologous or OD ART, we observed that OD women were older than autologous,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001. Overweight and obesity prevalence was higher in OD group; waist and WHR were significantly higher in autologous than in OD group (75% vs. 57%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.005, and 91.8% vs. 34.6%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.01, respectively). We observed a statistically significant unfavorable risk profile in OD in comparison to autologous women (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.003); in particular, 60% of OD women carried 3\u20135 CV risk factors, and 8.3% carried at least six CV risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The experience of an internal medicine clinic at the ART center strongly underlies the relevance of a careful medical evaluation before attempting ART, and suggests the opportuneness of a structured internal medicine clinic in every gynecology setting to better frame risk profile.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2018.6981","type":"journal-article","created":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T11:13:12Z","timestamp":1529061192000},"page":"1285-1292","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Assisted Reproductive Technology, Comorbidities, and Cardiovascular Risk: The Experience of an Italian Center"],"prefix":"10.1177","volume":"27","author":[{"given":"Cinzia","family":"Fatini","sequence":"first","affiliation":[{"name":"University of Florence","place":["Italy"]},{"name":"Careggi University Hospital","place":["Italy"]},{"name":"Careggi University Hospital","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Cirillo","sequence":"additional","affiliation":[{"name":"University of Florence","place":["Italy"]},{"name":"Careggi University Hospital","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elisabetta","family":"Coccia","sequence":"additional","affiliation":[{"name":"Careggi University Hospital","place":["Italy"]},{"name":"University of Florence","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,10,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2015.08.015"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.160744"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1582444"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.05.085"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-016-0836-8"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2017.07.021"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e8632"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.13147"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmt028"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.07.005"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.07.1078"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12945"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.09.007"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-016-0211-8"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew060"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs092"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67402-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2009.70"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw272"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(94)90106-6"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.102.10.1082"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01753.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2015.1115059"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.0000442009.06663.48"},{"key":"e_1_3_3_26_2","first-page":"e29","article-title":"on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics\u20142015 update: A report from the American Heart Association in Circulation","volume":"131","author":"Mozaffarian D","year":"2015","unstructured":"Mozaffarian D, , Benjamin EJ, , Go AS, et al. on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics\u20142015 update: A report from the American Heart Association in Circulation. Circulation, 2015; 131:e29\u2013e322.","journal-title":"Circulation"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.02.005"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.101873"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2014.06.024"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.03.031"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.8.2817"},{"key":"e_1_3_3_32_2","first-page":"171","article-title":"Risk factors for venous thrombosis: Prevalence, risk, and interaction","volume":"34","author":"Rosendaal FR","year":"1997","unstructured":"Rosendaal FR. Risk factors for venous thrombosis: Prevalence, risk, and interaction. Semin Hematol, 1997; 34:171\u2013187.","journal-title":"Semin Hematol"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.02.012"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2007.05.023"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.10.038"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096237"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.03.004"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.07.002"}],"container-title":["Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jwh.2018.6981","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2018.6981","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2018.6981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:48:33Z","timestamp":1777657713000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jwh.2018.6981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1089\/jwh.2018.6981"],"URL":"https:\/\/doi.org\/10.1089\/jwh.2018.6981","relation":{},"ISSN":["1540-9996","1931-843X"],"issn-type":[{"value":"1540-9996","type":"print"},{"value":"1931-843X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}