{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:41:55Z","timestamp":1777916515153,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Spontaneous preterm delivery (sPTD) is associated with a twofold increased risk of future maternal cardiovascular disease. We hypothesized that women with sPTD would demonstrate greater vascular dysfunction postpartum compared to women with term delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      In a case-controlled, matched pilot study, we enrolled 20 women with sPTD (gestation \u226434 weeks), and 20 term control women (gestation \u226539 weeks) were matched for age (\u00b15 years), parity, ethnicity, and route of delivery. Vascular function, serum lipids, C-reactive protein, and interleukin-6 were completed within 24\u201372 hours postpartum. Statistical analysis included paired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests based on match and mixed effects linear regression models and adjusted for potential confounders.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age for sPTD and term controls was 33\u2009\u00b1\u20096 years and 32\u2009\u00b1\u20096 years, respectively. Women with sPTD had significantly lower augmentation index-75 (24.1%\u2009\u00b1\u200916.1% vs. 39.9%\u2009\u00b1\u200915.2%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001) and central pulse pressure (29.1\u2009\u00b1\u20095.4\u2009mmHg vs. 34.6\u2009\u00b1\u20094.7\u2009mmHg,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.004), but no difference in pulse wave velocity (5.1\u2009\u00b1\u20091.6\u2009m\/s vs. 5.6\u2009\u00b1\u20091.5\u2009m\/s,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.12) compared to controls. Women with sPTD had significantly lower high-density lipoprotein cholesterol (59.4\u2009\u00b1\u200912.5\u2009mg\/dL vs. 67.6\u2009\u00b1\u200913.1\u2009mg\/dL,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.035) compared to controls. Analysis of chorioamnionitis and magnesium sulfate did not alter the results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Women with sPTD have signs of lower smooth muscle tone in the early postpartum period compared to women with term delivery. Further research is required to understand mechanistic pathways in sPTD and future maternal cardiovascular disease risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2018.7427","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T14:24:50Z","timestamp":1565187890000},"page":"1522-1528","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Vascular Function and Serum Lipids in Women with Spontaneous Preterm Delivery and Term Controls"],"prefix":"10.1177","volume":"28","author":[{"given":"Margo B.","family":"Minissian","sequence":"first","affiliation":[{"name":"Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California."},{"name":"Department of Nursing Research, Brawerman Nursing Institute, Cedars-Sinai Medical Center, Los Angeles, California."},{"name":"School of Nursing, University of California, Los Angeles, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Kilpatrick","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chrisandra L.","family":"Shufelt","sequence":"additional","affiliation":[{"name":"Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo-Ann","family":"Eastwood","sequence":"additional","affiliation":[{"name":"School of Nursing, University of California, Los Angeles, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendie","family":"Robbins","sequence":"additional","affiliation":[{"name":"School of Nursing, University of California, Los Angeles, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn J.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Central Coast Perinatology, Santa Barbara, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Burnes Bolton","sequence":"additional","affiliation":[{"name":"Department of Nursing Research, Brawerman Nursing Institute, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary-Lynn","family":"Brecht","sequence":"additional","affiliation":[{"name":"School of Nursing, University of California, Los Angeles, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet","family":"Wei","sequence":"additional","affiliation":[{"name":"Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Galen","family":"Cook-Wiens","sequence":"additional","affiliation":[{"name":"Biostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn V.","family":"Doering","sequence":"additional","affiliation":[{"name":"School of Nursing, University of California, Los Angeles, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Noel","family":"Bairey Merz","sequence":"additional","affiliation":[{"name":"Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,11,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000366"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.01.072"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181567f96"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2010.05.007"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.05.041"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11183"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.04.024"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2011.3013"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7323.1213"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03406-1"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.156810"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2013.4248"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000090"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.031403"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl254"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq024"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328336c8e9"},{"key":"e_1_3_3_19_2","first-page":"831","article-title":"[Radial augmentation index is associated with cardiovascular risk and arterial stiffness]","volume":"50","author":"Xiao WK","year":"2011","unstructured":"Xiao WK, , Ye P, , Luo LM, , Liu DJ, , Wu HM. [Radial augmentation index is associated with cardiovascular risk and arterial stiffness]. Zhonghua Nei Ke Za Zhi, 2011; 50:831\u2013835.","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0b013e32832941ce"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12145"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006134"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e318197c392"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjhyper.2004.10.009"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001573-200209000-00016"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.089078"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.886655"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000033"},{"key":"e_1_3_3_29_2","first-page":"284","article-title":"Preterm labor: Placental pathology and clinical correlation","volume":"94","author":"Germain AM","year":"1999","unstructured":"Germain AM, , Carvajal J, , Sanchez M, , Valenzuela GJ, , Tsunekawa H, , Chuaqui B. Preterm labor: Placental pathology and clinical correlation. Obstet Gynecol, 1999; 94:284\u2013289.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.37.6.1429"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.recesp.2011.07.009"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003319715590056"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2015.5414"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12398"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11154"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.3181\/0902-RM-88"},{"key":"e_1_3_3_37_2","volume-title":"Creasy and Resnik's maternal-fetal medicine: Principles and practice","author":"Creasy R","year":"2013","unstructured":"Creasy R, , Resnik R, , Iams J, , Lockwood C, , Moore T, , Greene M. Creasy and Resnik's maternal-fetal medicine: Principles and practice, 7th ed. Philadelphia: Saunders, 2013.","edition":"7"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.12.3.267"},{"key":"e_1_3_3_39_2","volume-title":"Obsteterics normal and problem pregnancies","author":"Simhan HN","year":"2017","unstructured":"Simhan HN, , Iams JD, , Romero R. Obsteterics normal and problem pregnancies, 7th ed. Philadelphia: Elsevier, 2017.","edition":"7"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2010.02.003"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.06.080"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm273"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199816121-00033"}],"container-title":["Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jwh.2018.7427","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2018.7427","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2018.7427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T17:49:51Z","timestamp":1777657791000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jwh.2018.7427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":42,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1089\/jwh.2018.7427"],"URL":"https:\/\/doi.org\/10.1089\/jwh.2018.7427","relation":{},"ISSN":["1540-9996","1931-843X"],"issn-type":[{"value":"1540-9996","type":"print"},{"value":"1931-843X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]}}}