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Owing to their unique physiological mechanism of action, many of these medications can also be used to prevent cancer and treat multiple general medical conditions that are common in women. We performed a comprehensive literature search. This article will describe the specific mechanisms of action and summarize the available data documenting how hormonal contraceptives can prevent ovarian and uterine cancer and be used to treat women with a variety of gynecological and nongynecological conditions such as endometriosis, uterine fibroids, heavy menstrual bleeding, polycystic ovary syndrome, acne, and migraines. Contraceptive methods containing estrogen and progestin can be used for a wide variety of medical issues in women.<\/jats:p>","DOI":"10.1089\/jwh.2019.7731","type":"journal-article","created":{"date-parts":[[2020,3,10]],"date-time":"2020-03-10T16:53:56Z","timestamp":1583859236000},"page":"937-943","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Beyond Birth Control: Noncontraceptive Benefits of Hormonal Methods and Their Key Role in the General Medical Care of Women"],"prefix":"10.1177","volume":"29","author":[{"given":"Sarina","family":"Schrager","sequence":"first","affiliation":[{"name":"Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnolia","family":"Larson","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jensena","family":"Carlson","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Ledford","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah B.","family":"Ehrenthal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."},{"name":"Department of Gynecology and Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,9]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Current contraceptive status among women aged 15\u201344: United States, 2011\u20132013. 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