{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T11:54:06Z","timestamp":1791633246632,"version":"4.3.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To assess associations between infertility and health-related quality of life and medical comorbidities in U.S. women Veterans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This cross-sectional observational study involved computer-assisted telephone interviews of Veterans Administration-enrolled women between ages 21 and 52 years. Patients were analyzed in two groups by self-reported history of infertility. Outcomes included health-related quality of life as measured by the short-form 12-item interview (SF-12) physical and mental component summary (PCS and MCS) scores, depression, post-traumatic stress disorder (PTSD), eating disorders, fibromyalgia, other chronic pain, cardiovascular disease risk factors, and cancer. Age-adjusted\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      -values and adjusted odds ratios (AORs) were calculated using individual multivariate regression models to control for significant confounding covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the 996 women veterans included, 179 (18.0%) reported a history of infertility. Infertility was associated with worse perceived physical health as determined by the SF-12 PCS [beta coefficient (B) \u22123.23 (\u22125.18 to \u22121.28)] and fibromyalgia [AOR 1.97 (1.22 to 3.19)]. Infertility was also associated with higher rates of depression, other chronic pain, and cancer, which remained significant after adjusting for age (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.021,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.016, and\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.045, respectively); however, no association for all was seen after adjustment for other significant covariates. There was no difference in Veterans' mental health using the SF-12 MCS, nor differences seen in PTSD or eating disorder rates, or in cardiovascular risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This novel investigation in U.S. women Veterans found worse physical health-related quality of life and increased rates of fibromyalgia among women reporting a history of infertility, adding to the growing literature on infertility as a marker for overall poorer health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2019.7798","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T10:32:01Z","timestamp":1574418721000},"page":"412-419","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Infertility and Health-Related Quality of Life in United States Women Veterans"],"prefix":"10.1177","volume":"29","author":[{"given":"Abigail C.","family":"Mancuso","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen M.","family":"Summers","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle A.","family":"Mengeling","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa."},{"name":"Center for Comprehensive Access and Delivery Research and Evaluation (CADRE), Iowa City Veteran Affairs Health Care System, Iowa City, Iowa."},{"name":"VA Office of Rural Health (ORH), Veterans Rural Health Resource Center\u2014Iowa City Veterans Affairs Health Care System, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Torner","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Iowa College of Public Health, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginny L.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne G.","family":"Sadler","sequence":"additional","affiliation":[{"name":"Center for Comprehensive Access and Delivery Research and Evaluation (CADRE), Iowa City Veteran Affairs Health Care System, Iowa City, Iowa."},{"name":"Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,3,17]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"1","article-title":"Infertility service use in the United States: Data from the National Survey of Family Growth, 1982\u20132010","volume":"73","author":"Chandra A","year":"2014","unstructured":"Chandra A, , Copen CE, , Stephen EH. 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