{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:35:36Z","timestamp":1787726136584,"version":"build-2784847793"},"reference-count":41,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Quality of life (QOL) and psychological health has been reported to be decreased among women with gynecological conditions such as uterine fibroids (UFs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Women enrolled in the Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry, receiving procedural therapy for symptomatic UFs, were eligible for this analysis if they completed a series of health-related QOL surveys administered at three time points (baseline, 6\u201312 weeks postprocedure, and 1 year postprocedure;\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20091486). Ethical approval for this study was obtained at each recruiting site and the coordinating center (NCT02260752,\n                      <jats:uri xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:uri>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      More than 26% (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009393) of women reported moderate anxiety\/depression on the baseline anxiety\/depression domain of the Euro-QOL 5-dimension instrument. At both the 6\u201312 weeks and 1-year postprocedural follow-up, there was significant improvement in the UF QOL symptom severity score (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), the total UF symptom QOL score (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and the Euro-QOL 5-dimension visual analog scale (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.004) compared with the preprocedural baseline scores. The reporting of anxiety\/depression decreased by 66.4% among women who were at baseline, whereas 5.6% of women previously reporting no anxiety\/depression reported anxiety\/depression at the 1-year follow-up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>UF symptoms were more severe among women reporting anxiety\/depression at baseline. At the 1-year follow-up, health-related QOL scores improved among all women and the prevalence of anxiety\/depression decreased in most, but not all women, whereas severity of anxiety\/depression worsened in a small percentage of women (5.6%). Overall, these results suggest that UF treatment improves symptoms of anxiety\/depression associated with symptomatic UFs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2020.8915","type":"journal-article","created":{"date-parts":[[2021,6,8]],"date-time":"2021-06-08T16:02:53Z","timestamp":1623168173000},"page":"415-424","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Anxiety, Depression, and Quality of Life After Procedural Intervention for Uterine Fibroids"],"prefix":"10.1177","volume":"31","author":[{"given":"Kedra","family":"Wallace","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"Wise","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanda Kay","family":"Nicholson","sequence":"additional","affiliation":[{"name":"Center for Women's Health Research, Department of Obstetrics and Gynecology, UNC School of Medicine, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Preston","family":"Parry","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuaiqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9854-5866","authenticated-orcid":false,"given":"Shannon","family":"Laughlin-Tommaso","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Jacoby","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco, San Francisco, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond M.","family":"Anchan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Diamond","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Augusta University, Augusta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sateria","family":"Venable","sequence":"additional","affiliation":[{"name":"Fibroid Foundation, Bethesda, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Shiflett","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, Mississippi, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesa R.","family":"Wegienka","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George Larry","family":"Maxwell","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and 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