{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:03:02Z","timestamp":1791655382763,"version":"4.3.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pain crises in sickle cell disease (SCD) lead to high rates of health care utilization. Historically, women have reported higher pain burdens than men, with recent studies showing a temporal association between pain crisis and menstruation. However, health care utilization patterns of SCD women with menstruation-associated pain crises have not been reported. We studied the frequency, severity, and health care utilization of menstruation-associated pain crises in SCD women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A multinational, cross-sectional cohort study of the SCD phenotype was executed using a validated questionnaire and medical chart review from the Consortium for the Advancement of Sickle Cell Research (CASiRe) cohort. Total number of pain crises, emergency room\/day hospital visits, and hospitalizations were collected from a subcohort of 178 SCD women within the past 6 months and previous year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-nine percent of women reported menstruation-associated pain crises in their lifetime. These women were significantly more likely to be hospitalized compared with those who did not (mean 1.70 vs. 0.67,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0005). Women reporting menstruation-associated pain crises in the past 6 months also experienced increased hospitalizations compared with those who did not (mean 1.71 vs. 0.75,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0016). Forty percent of women reported at least four menstruation-associated pain crises in the past 6 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Nearly 40% of SCD women have menstruation-associated pain crises. Menstruation-associated pain crises are associated with high pain burden and increased rates of hospitalization. Strategies are needed to address health care disparities within gynecologic care in SCD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.0023","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T13:03:30Z","timestamp":1701090210000},"page":"1284-1291","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Pain Frequency and Health Care Utilization Patterns in Women with Sickle Cell Disease Experiencing Menstruation-Associated Pain Crises"],"prefix":"10.1177","volume":"32","author":[{"given":"Catherine","family":"Segbefia","sequence":"first","affiliation":[{"name":"Department of Child Health, University of Ghana Medical School, Accra, Ghana."},{"name":"Department of Child Health, Korle Bu Teaching Hospital, Accra, Ghana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jillian","family":"Campbell","sequence":"additional","affiliation":[{"name":"Center for Cancer and Blood Disorders, Children's National Hospital, Washington, District of Columbia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immacolata","family":"Tartaglione","sequence":"additional","affiliation":[{"name":"Department of Women, Child and General and Specialized Surgery, University of Campania \u201cLuigi Vanvitelli,\u201d Naples, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia Vicky","family":"Asare","sequence":"additional","affiliation":[{"name":"Department of Hematology, Korle-Bu Teaching Hospital, Accra, Ghana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biree","family":"Andemariam","sequence":"additional","affiliation":[{"name":"Division of Hematology-Oncology, New England Sickle Cell Institute, Neag Comprehensive Cancer Center, University of Connecticut, Farmington, Connecticut, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Zempsky","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Colombatti","sequence":"additional","affiliation":[{"name":"Department of Women's and Child Health, Clinic of Pediatric Hematology Oncology, Azienda Ospedaliera-Universit\u00e0 di Padova, Padova, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gifty Dankwah","family":"Boatemaa","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Ghana Medical School, University of Ghana, Accra, Ghana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Boruchov","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudha","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Child Health, Korle Bu Teaching Hospital, Accra, Ghana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connie M.","family":"Piccone","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology\/Oncology, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashya","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haikel","family":"Haile","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Wilson","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatimah","family":"Farooq","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah","family":"Urbonya","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, University of Michigan, Ann Arbor, Michigan, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Rivers","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California San Francisco, San Francisco, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Manwani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxiang","family":"Gai","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Study Methodology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredericka","family":"Sey","sequence":"additional","affiliation":[{"name":"Ghana Institute of Clinical Genetics, Korle Bu Teaching Hospital, Accra, Ghana."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baba","family":"Inusa","sequence":"additional","affiliation":[{"name":"Department of Pediatric Haematology, Evelina Children's Hospital, Guy's and St. Thomas NHS Trust, College of Nursing, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Antwi-Boasiako","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Ghana Medical School, University of Ghana, Accra, Ghana."},{"name":"College of Health Nursing, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crawford","family":"Strunk","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Foundation, Cleveland, OH, 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