{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:01:17Z","timestamp":1779375677317,"version":"3.53.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Maximizing preconception health is an important strategy to prevent preeclampsia in pregnancy. Preeclampsia remains a significant cause of maternal and fetal morbidity and mortality. We examined the associations between preconception maternal body weight, body mass index (BMI), and blood pressure with preeclampsia and its related outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective review of 11,214 live births from 6 months preconception during 2009\u20132018 in the University of Washington medical system. Outcomes were analyzed using chi-square, analysis of variance, and\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests. Binary logistic regression was performed to examine associations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 11,214 births, 1,539 (13.7%) were complicated by preeclampsia. Individuals with preeclampsia weighed more and had higher blood pressure from 6 months preconception to at least 6 months of pregnancy compared with those without preeclampsia (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Persons with prepregnancy systolic blood pressure (SBP) \u2265130\u2009mmHg were 3.2 times more likely to develop preeclampsia than those with SBP &lt;130\u2009mmHg (adjusted odds ratio [aOR]\u2009=\u20093.24, 95% confidence interval [CI]\u2009=\u20092.37\u20134.43). Women with prepregnancy BMI \u226530\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      were 2.3 times more likely to develop preeclampsia (aOR\u2009=\u20092.31, 95% CI\u2009=\u20091.72\u20133.10) than those with BMI &lt;30\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Mothers with preeclampsia were more likely to deliver preterm (29% vs. 13.8%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and have neonates with 5-minute Apgar scores &lt;8 (22.1% vs. 12.1%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.02) and lower preterm birthweights (1,909\u2009g, 95% CI\u2009=\u20091,813\u20132,004\u2009g vs. 2,057\u2009g, 95% CI\u2009=\u20091,989\u20132,123\u2009g).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Maternal obesity and elevated blood pressure from 6 months preconception to 6 months of pregnancy were associated with preeclampsia, resulting in maternal and fetal complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.0083","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T16:54:22Z","timestamp":1701968062000},"page":"1374-1380","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Associations of Preconception Body Weight, Body Mass Index, and Hypertension with Preeclampsia"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0941-2146","authenticated-orcid":false,"given":"Priyanka","family":"Gaur","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Power","sequence":"additional","affiliation":[{"name":"Center for Species Survival, Smithsonian's National Zoo and Conservation Biology Institute, Washington, District of Columbia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Schulkin","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, University of Washington School of Medicine, Seattle, Washington, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angie C.","family":"Jelin","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,12,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2013.05.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2011.01.006"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0029-7844(00)00938-8"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17493"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.385301.BE"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41440-020-0438-9"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.14875"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.771738"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00178.2015"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011626"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.10999"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.18502\/ijrm.v17i7.4857"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-018-1687-3"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu12092681"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2004.12.008"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1081167"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-014-0422-y"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000451"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12047"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20088"},{"issue":"1","key":"e_1_3_3_22_2","first-page":"82","article-title":"Associations of the pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in Taiwanese women","volume":"21","author":"Tsai IH","year":"2012","unstructured":"Tsai IH, , Chen CP, , Sun FJ, et al. Associations of the pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in Taiwanese women. Asia Pacific J Clin Nutr, 2012; 21(1):82\u201387.","journal-title":"Asia Pacific J Clin Nutr"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-017-1567-2"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.01.015"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003020"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7356.157"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2201295"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000213"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0119018"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2016.09.007"},{"key":"e_1_3_3_31_2","unstructured":"U.S. Census Bureau QuickFacts. Available from: https:\/\/data.census.gov\/table [Last accessed: August1 2023]."},{"key":"e_1_3_3_32_2","unstructured":"U.S. Census Bureau QuickFacts. Available from: https:\/\/www.census.gov\/quickfacts\/fact\/table\/seattlecitywashington\/PST045222 [Last accessed: August1 2023]."},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000696"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2016.04.020"}],"container-title":["Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jwh.2023.0083","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2023.0083","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2023.0083","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:32:37Z","timestamp":1778909557000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jwh.2023.0083"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,8]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,1]]}},"alternative-id":["10.1089\/jwh.2023.0083"],"URL":"https:\/\/doi.org\/10.1089\/jwh.2023.0083","relation":{},"ISSN":["1540-9996","1931-843X"],"issn-type":[{"value":"1540-9996","type":"print"},{"value":"1931-843X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,8]]}}}