{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:48:03Z","timestamp":1777916883134,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Uterine cavity abnormalities contribute to infertility. The purpose of this study was to evaluate the incidence, recurrence rates, and risk factors for uterine cavity abnormalities in women undergoing infertility workup and treatment, focusing on the utility of routinely repeated imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective cohort study at single academic medical center of 833 infertile women who had uterine cavity evaluations performed at least 9 months apart.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of 833 eligible patients, 664 (79.7%) had normal initial imaging and 169 (20.3%) had abnormal initial imaging. Among the former, 10% had abnormal uterine cavity on repeat saline infusion sonohysterography (SIS); among the latter, 32% had abnormal repeat SIS [Chi-square\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.0001, risk ratio 2.30 (95% confidence interval 1.85\u20132.86)]. On average, 23.1\u2009\u00b1\u200913.6 months passed between studies. Regardless of initial imaging findings, women with abnormal repeat SIS were older than those with normal repeat SIS, with no difference in time elapsed between studies. There were no associations between repeat imaging outcomes and body mass index, uterine instrumentation, number of treatment cycles, or maximum peak estradiol levels in a single cycle between studies. There was no difference in live birth rate among cycles started within 1 year after repeat SIS across groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Uterine cavity abnormalities were found in 10% of patients on repeat imaging despite initially normal testing. No risk factors for cavity abnormality on repeat imaging were identified besides age and prior abnormality. It would be prudent to continue performing routine repeat uterine cavity evaluation for women undergoing fertility treatment, particularly if corrective measures had been taken in the past.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.0302","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T11:50:20Z","timestamp":1703073020000},"page":"171-177","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Utility of Repeat Uterine Cavity Evaluation in the Infertility Workup"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1973-1714","authenticated-orcid":false,"given":"Andrey V.","family":"Dolinko","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Providence, Rhode Island, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8165-3457","authenticated-orcid":false,"given":"Valery A.","family":"Danilack","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA."},{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben J.","family":"Alvero","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Stanford University Medical Center and School of Medicine, Sunnyvale, California, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria V.","family":"Snegovskikh","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women and Infants Hospital of Rhode Island, Providence, Rhode Island, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,2,13]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0887-2171(95)90035-7"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx019"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmu057"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2017.06.034"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-007-0460-z"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.03.067"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0015-0282(98)00045-4"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deq150"},{"issue":"2","key":"e_1_3_4_12_2","first-page":"103","article-title":"1000 office-based hysteroscopies prior to in vitro fertilization: Feasibility and findings","volume":"8","author":"Hinckley MD","year":"2004","unstructured":"Hinckley MD, , Milki AA. 1000 office-based hysteroscopies prior to in vitro fertilization: Feasibility and findings. 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