{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:34:20Z","timestamp":1790883260064,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Leiomyomas are associated with lower urinary tract symptoms (LUTS), but more specific characterization of their impact on LUTS is needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This is a retrospective cohort study of 202 participants (101 per group) who underwent hysterectomy for leiomyomas versus abnormal uterine bleeding nonclassified (AUB-N) from July 2015 to May 2019. Baseline demographics, leiomyoma characteristics, and presence of baseline LUTS were collected. The main objective was to compare the prevalence of LUTS between these two groups. Secondary objectives were to analyze the association between leiomyoma characteristics and the prevalence of LUTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There was no difference in baseline prevalence of LUTS between the hysterectomy for leiomyoma versus AUB-N groups (42.6% vs. 45.5%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.67). When examining the entire study cohort of participants, irrespective of hysterectomy indication, leiomyoma size &gt;6 cm was associated with an increased prevalence of LUTS when compared with leiomyoma &lt;6 cm (64.9% vs. 40.4%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02), and specifically difficulty passing urine (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02), nocturia (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.04), and urinary frequency (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.04). When controlling for age, body mass index, parity, chronic pelvic pain, and diabetes, leiomyomas &gt;6 cm remained significantly associated with the presence of LUTS (odds ratio 3.1, 95% confidence interval = 1.2\u20138.3) when compared with leiomyoma &lt;6 cm. Presence of &gt;1 leiomyoma was associated with urinary frequency (67.9% vs. 32.1%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.02) when compared with \u22641 leiomyoma. Anterior location and uterine volume were not associated with a difference in LUTS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>LUTS are prevalent in those planning hysterectomy for leiomyoma and AUB-N. Leiomyomas &gt;6 cm are associated with the presence of LUTS. Future studies should evaluate change in LUTS following hysterectomy for leiomyomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.0988","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T08:26:40Z","timestamp":1712219200000},"page":"798-804","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Prevalence of Lower Urinary Tract Symptoms in Women Planning to Undergo Hysterectomy for Uterine Leiomyoma and Abnormal Uterine Bleeding"],"prefix":"10.1177","volume":"33","author":[{"given":"Ijeoma","family":"Agu","sequence":"first","affiliation":[{"name":"Division of Urogynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeshree","family":"Das","sequence":"additional","affiliation":[{"name":"School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Geller","sequence":"additional","affiliation":[{"name":"Division of Urogynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin T.","family":"Carey","sequence":"additional","affiliation":[{"name":"Division of Minimally Invasive Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Chu","sequence":"additional","affiliation":[{"name":"Division of Urogynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13102"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2018.7076"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0b013e31820c99a9"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0015-0282(02)04539-9"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.02.029"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2021.05.032"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2009.1396"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0b013e3181ee6864"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-013-2295-4"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.7748\/nop.2021.e1305"},{"key":"e_1_3_5_12_2","unstructured":"Pelvic Health Questionnaire. 2019. 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