{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T17:39:55Z","timestamp":1793468395068,"version":"4.5.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Uterine-sparing surgery for pelvic organ prolapse (POP) repair has shown good results, but the potential negative implications of leaving the uterus in place are yet to be fully defined. We aimed to assess the risk of unanticipated abnormal gynecological pathology at the time of reconstructive pelvic surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective consecutive case series including women who underwent vaginal hysterectomy for POP repair at a tertiary medical center in 2006\u20132020. All patients were offered a free Pap smear test at the age of 65 years as part of a national screening program. Transvaginal ultrasound was routinely performed preoperatively. Standard 3 pedicle hysterectomy was performed with\/without bilateral salpingo-oophorectomy (BSO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The study comprised 462 women of mean age 63 \u00b1 9.3 years without previous known malignant or premalignant pathology. Benign pathology was observed in 286 patients (61.9%). Endometrial malignancy was found in three patients (0.7%) and significant premalignant pathology in 15 patients (3.2%), including cervical intraepithelial neoplasia stage 2\u20133 in seven patients (1.5%) and complex hyperplasia with atypia in eight patients (1.7%). All these pathologies were found in postmenopausal women. None had preoperative clinical symptoms or endometrial thickness of \u22655 mm on preoperative ultrasound. In the 35 patients after BSO, adnexal findings were normal (77.2%) or benign (22.8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Premenopausal women with uterovaginal prolapse and normal preoperative evaluation have a minimal risk of significant abnormal uterine pathology. In postmenopausal women, the risk of unanticipated malignant uterine pathology is 0.7% and 3.2% for significant premalignancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.1019","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T09:14:20Z","timestamp":1714727660000},"page":"1423-1427","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Abnormal Pathology Following Vaginal Hysterectomy for Pelvic Organ Prolapse Repair"],"prefix":"10.1177","volume":"33","author":[{"given":"Yossi","family":"Geron","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"From","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoav","family":"Peled","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil","family":"Zeevi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Matot","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapir","family":"Nachshon","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haim","family":"Krissi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center \u2013 Beilinson Hospital, Petah Tikva, Israel."},{"name":"Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181f73729"},{"key":"e_1_3_6_3_2","unstructured":"U.S. Food and Drug Administration. FDA takes action to protect women's health orders manufacturers of surgical mesh intended for transvaginal repair of pelvic organ prolapse to stop selling all devices. Available from: https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-takes-action-protect-womens-health-orders-manufacturers-surgical-mesh-intended-transvaginal"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-005-1346-x"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-003-1084-x"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001920170017"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-011-1635-5"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2006.04.009"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-005-0019-0"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000000903"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12306"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-132-10-200005160-00009"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21955"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1101-9"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.01.077"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12033"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pgp.0000101142.79462.be"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1694-2"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-014-2516-5"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2016.27.e8"}],"container-title":["Journal of Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/jwh.2023.1019","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2023.1019","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/jwh.2023.1019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:00:40Z","timestamp":1777658440000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/jwh.2023.1019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":19,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1089\/jwh.2023.1019"],"URL":"https:\/\/doi.org\/10.1089\/jwh.2023.1019","relation":{},"ISSN":["1540-9996","1931-843X"],"issn-type":[{"value":"1540-9996","type":"print"},{"value":"1931-843X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]}}}