{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:30:10Z","timestamp":1793115010108,"version":"4.5.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T00:00:00Z","timestamp":1704758400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Although the risk of pregnancy-related morbidity and mortality in people with sickle cell disease (SCD) is well established, limitations in data sources and heterogeneity in outcome reporting hinder the ability to make meaningful comparisons between historical and contemporary populations. This study used a national administrative claims database to compare pregnancy outcomes in people with SCD between 2006\u20132011 and 2012\u20132018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Pregnant females aged 16\u201344 years with SCD were identified from the Centers for Medicare and Medicaid Service Analytic eXtract, along with a control cohort of pregnant people. People were followed from first identified pregnancy until one year postpartum. Outcomes of interest were identified with ICD-9 or 10 codes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We included 6,388 people with SCD and 17,278 controls in analyses. Preeclampsia\/eclampsia, hypertension, thrombosis, poor fetal growth, preterm delivery, and postpartum hemorrhage were all more common in people with SCD compared with controls. Maternal death occurred in 0.5% of people with SCD versus &lt;0.1% in those without SCD (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.001). When comparing infant deliveries in 2006\u20132011 to those occurring in 2012\u20132018, all pregnancy-related complications except preterm delivery, including maternal death, occurred at similar or higher frequencies in more recent years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Between 2006 and 2018, maternal death occurred in approximately 1 out of every 200 publicly insured people with SCD in the year following infant delivery. Our work confirms, on a national-level, that pregnancy-related outcomes in people with SCD in the United States have not improved with time, and that some complications have in fact increased in frequency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2023.1109","type":"journal-article","created":{"date-parts":[[2024,10,31]],"date-time":"2024-10-31T04:51:50Z","timestamp":1730350310000},"page":"21-26","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Trends in Pregnancy Outcomes in People with Sickle Cell Disease and Medicaid Insurance (2006\u20132018)"],"prefix":"10.1177","volume":"34","author":[{"given":"Sarah H.","family":"O\u2019Brien","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology\/BMT, College of Medicine, Nationwide Children\u2019s Hospital and The Ohio State University, Columbus, Ohio, USA."},{"name":"Center for Child Health Equity and Outcomes Research, Abigail Wexner Research Institute at Nationwide Children\u2019s Hospital, Columbus, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Stanek","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology\/BMT, College of Medicine, Nationwide Children\u2019s Hospital and The Ohio State University, Columbus, Ohio, USA."},{"name":"Biostatistics Resource at Nationwide Children\u2019s Hospital, Columbus, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"House","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, College of Medicine, Nationwide Children\u2019s Hospital and The Ohio State University, Columbus, Ohio, USA."},{"name":"Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Cronin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Creary","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology\/BMT, College of Medicine, Nationwide Children\u2019s Hospital and The Ohio State University, Columbus, Ohio, USA."},{"name":"Center for Child Health Equity and Outcomes Research, Abigail Wexner Research Institute at Nationwide Children\u2019s Hospital, Columbus, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea H.","family":"Roe","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara K.","family":"Vesely","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, Hudson College of Public Health, The University of Oklahoma, Oklahoma City, Oklahoma, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,1,9]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17658"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0033354919881438"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-11-607317"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/M14-1884"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.10517"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26818"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.54552"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2022007089"},{"key":"e_1_3_5_10_2","unstructured":"Chronic Conditions Warehouse. Other Chronic Health Mental Health and Potentially Disabling Conditions Algorithms. Available from: https:\/\/www2.ccwdata.org\/documents\/10280\/19140001\/oth-cond-algo-scd.pdf; [Last accessed: December06 2023]."},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0033354919839072"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.25432"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.29245\/2572-9411\/2017\/4.1124"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2016.1241"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2019.01835"},{"key":"e_1_3_5_16_2","unstructured":"Centers for Disease Control and Prevention. Pregnancy Mortality Surveillance System. Available from: https:\/\/www.cdc.gov\/maternal-mortality\/php\/pregnancy-mortality-surveillance\/?CDC_AAref_Val=https:\/\/www.cdc.gov\/reproductivehealth\/maternal-mortality\/pregnancy-mortality-surveillance-system.htm; [Last accessed: June18 2024]."},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13936"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.46864"},{"issue":"216","key":"e_1_3_5_19_2","first-page":"1","article-title":"Births in the United States, 2013","author":"Martin JA","year":"2015","unstructured":"Martin JA, , Hamilton BE, , Osterman MJ. Births in the United States, 2013. 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