{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:49:40Z","timestamp":1777916980705,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Women's Health"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Ovarian aging, often leads to increased use of a donor oocyte, which is associated with greater risk for age-related diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      : To evaluate the association between women conceiving through oocyte donation (OD) and future cancer-related morbidity, as compared with women conceiving through IVF (\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      fertilization) with autologous oocytes (AO), spontaneous conceptions (SC), and nulliparas.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective, cohort study was based on the electronic health records of a very large health maintenance organization. The cohort included mothers who delivered before age 45, during 2000\u20132019. The index date for surveillance was the delivery date of the relevant pregnancy. Each woman from the OD group was matched to a woman the same age at delivery and with the same number of children. Cancer diagnosis was the main outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Matching: 664 OD cases to 664 AO, 700 OD cases to 700 SC, and 700 OD cases to 700 nulliparas. Mean follow-up times were 8.9\u2009\u00b1\u20093.8 OD, 10 \u00b1 4.1 AO, and 6.4\u2009\u00b1\u20094.1 years SC. Cancer-related morbidity rates were comparable between OD and the other groups, but compared with nulliparas, a trend was noted (1.6% and 3.1%, respectively,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.07). Survival analysis curves were not significantly different, although a trend was shown in the curve comparing to nulliparity (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.07). In a Cox regression model corrected for BMI, smoking and hormone replacement therapy exposure, cancer in the OD group did not differ compared to the other groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Women conceiving through OD do not have increased risk for cancer-related morbidity in the decade following delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/jwh.2024.0248","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T11:15:44Z","timestamp":1724411744000},"page":"1730-1734","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cancer-Related Morbidity Among Patients Conceiving Through Oocyte Donation: A Healthcare Registry Cohort Study"],"prefix":"10.1177","volume":"33","author":[{"given":"Anat","family":"Hershko Klement","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aula","family":"Asali","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hila","family":"Shalev Ram","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-0051","authenticated-orcid":false,"given":"Einat","family":"Haikin-Herzberger","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roi","family":"Shlezinger","sequence":"additional","affiliation":[{"name":"Department of Statistics and Data Science, Hebrew University of Jerusalem, Jerusalem, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Wiser","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Netanella","family":"Miller","sequence":"additional","affiliation":[{"name":"IVF Unit, Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel."},{"name":"School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel."},{"name":"Mayanei Hayeshua Medical Center, IVF unit, Bnei Brak, 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